Phenols
Medchemexpress LLC m-PEG2-acid | 149577-05-9 | >98% | 1 G
m-PEG2-acid is a polyethylene glycol (PEG)-based PROTAC linker. It is primarily used in the synthesis of Proteolysis-Targeting Chimeras (PROTACs), which are molecules designed to exploit the intracellular ubiquitin-proteasome system. PROTACs achieve selective degradation of target proteins by linking them to an E3 ubiquitin ligase.
- PEG-based PROTAC linker
- Facilitates the synthesis of PROTACs
- Molecular weight of 148.16
- Chemical formula C6H12O4
- Appears as a colorless to light yellow liquid
- Density of 1.098 ±0.06 g/cm³
- Storage for pure form: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
eMolecules 2-Amino-4-(2,5-dimethylphenyl)thiophene-3-carbonitrile | 519016-81-0 | MFCD02244485 | 1g
Combi-Blocks | 2-Amino-4-(2,5-dimethylphenyl)thiophene-3-carbonitrile | 1g | 205395986 | QA-0906 | 95.000 | 519016-81-0 | MFCD02244485 | 228.310 | C13H12N2S
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BIOHIPPO h/m NRP1-sh-GFP/Luc
h/m NRP1-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Apexbio Technology LLC EZ Cap Mouse GM-CSF mRNA (m1Ψ) 1mg (1mg/mL)
GM-CSF mRNA encodes Granulocyte-Macrophage Colony-Stimulating Factor (CSF) produced by T cells macrophages endothelial cells and fibroblasts It stimulates the differentiation of hematopoietic stem cells in bone marrow into granulocytes and macrophages thereby enhancing the body s immune response capability GM-CSF not only promotes leukocyte production but also enhances their functions such as improving phagocytosis and antigen presentation abilities Clinically GM-CSF is used to treat certain types of leukopenia and serves as an adjuvant in cancer immunotherapy EZ Cap Mouse GM-CSF mRNA (m1 ) is provided at 1 mg/mL It expresses mouse-derived GM-CSF cytokine It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
eMolecules Ambeed / 2-Methoxy-5-methylphenol / 1g / 588342906 / A579324 / / 1195-09-1 / MFCD00040901 / 138.166 / C8H10O2
Ambeed / 2-Methoxy-5-methylphenol / 1g / 588342906 / A579324 / / 1195-09-1 / MFCD00040901 / 138.166 / C8H10O2
Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Medchemexpress LLC Contactin-3/CNTN3 M 10ug
Contactin-3/CNTN3 protein facilitates cell surface interactions in nervous system development promoting neurite outgrowth and interacting with PTPRG to regulate neuronal growth and connectivity Contactin-3/CNTN3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Contactin-3/CNTN3 protein expressed by HEK293 with C-His labeled tag
Cell Signaling Technology Neurofilament-M (E7Y8W) Mouse mAb 20 ul
Neurofilament-M (E7Y8W) Mouse mAb 20 ul
Medchemexpress LLC Contactin-3/CNTN3 M 5ug
Contactin-3/CNTN3 protein facilitates cell surface interactions in nervous system development promoting neurite outgrowth and interacting with PTPRG to regulate neuronal growth and connectivity Contactin-3/CNTN3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Contactin-3/CNTN3 protein expressed by HEK293 with C-His labeled tag
BIOHIPPO h/m FASN-sh-BSD
h/m FASN-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC Interleukin-24 (IL-24) | >95.0% | 10UG
Animal-Free IL-24 Protein, Mouse (His) is a recombinant mouse interleukin-24 expressed in Escherichia coli and supplied lyophilized with a C-terminal 6xHis tag for research use in cell culture and in vitro assays. The product is highly pure and biologically active, with characterization by SDS-PAGE and functional ED50 data.
BIOHIPPO h/m CD36-sh-BSD
h/m CD36-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m CD36 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse CD36 molecule (CD36) The shRNA has been validated to meet or exceed 70% CD36 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC m-PEG7-CH2CH2COOH | 1093647-41-6 | >99.39% | 25 G
m-PEG7-CH2CH2COOH (CAS No. 1093647-41-6) is a non-cleavable, PEG-based linker used in the synthesis of antibody-drug conjugates (ADCs) and as a PROTAC linker. It is an essential component for developing targeted therapeutics due to its role in connecting active pharmaceutical ingredients to targeting moieties.
- Recommended storage for pure form: -20°C for 3 years, 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month.
- Shipping at room temperature is acceptable if duration is less than 2 weeks.
- Chemically identified as 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid.
eMolecules 3-Amino-3-(3,4-dimethylphenyl)propanoic acid | 412925-16-7 | MFCD02663197 | 1g
Combi-Blocks | 3-Amino-3-(3,4-dimethylphenyl)propanoic acid | 1g | 517026543 | QZ-1019 | 97.000 | 412925-16-7 | MFCD02663197 | 193.246 | C11H15NO2
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eMolecules (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone | 1309241-34-6 | | 100mg
Ambeed | (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone | 100mg | 600830038 | A1362216 | | 1309241-34-6 | | 353.466 | C21H27N3O2
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