Phenols
![Medchemexpress LLC 7-[3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propoxy]-1H-quinolin-2-one hydrochloride | 1329509-60-5 | 99.0% | 427.97 g·mol⁻¹ | C24H30ClN3O2 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241642.png-250.jpg)
Medchemexpress LLC 7-[3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propoxy]-1H-quinolin-2-one hydrochloride | 1329509-60-5 | 99.0% | 427.97 g·mol⁻¹ | C24H30ClN3O2 | 1 MG
OPC 4392 hydrochloride is a small-molecule dopamine receptor modulator used in preclinical pharmacology research. It functions as a presynaptic dopamine autoreceptor agonist and a postsynaptic D2 receptor antagonist, and has been applied in animal studies to reverse reserpine-induced dopamine depletion and reduce apomorphine-induced behaviors.
- Acts as presynaptic dopamine autoreceptor agonist and postsynaptic D2 antagonist.
- Demonstrated efficacy in reversing reserpine-induced dopamine depletion in animal studies.
- Inhibits apomorphine-induced stereotypic and climbing behaviors in rodent models.
- High purity (98.99%) suitable for research applications.
- White to off-white solid, convenient for handling and formulation.
- Recommended sealed storage away from moisture; in solvent store at -80°C for long-term preservation.
Medchemexpress LLC 6-bromo-2-hydroxy-3-methoxybenzaldehyde | 20035-41-0 | MFCD00046152 | 100.0% | 231.04 | C8H7BrO3 | 1 ML
6-Bromo-2-hydroxy-3-methoxybenzaldehyde is a small-molecule research reagent reported as an inhibitor of IRE1α for studies of the unfolded protein response. It is supplied as a high-purity solid in multiple weights or as a 10 mM solution in DMSO, and is characterized by formula C8H7BrO3 and molecular weight 231.04.
- High purity (99.96%) suitable for biochemical and cellular assays.
- Available as solid (multiple sizes) and as a 10 mM solution in DMSO for convenience.
- Reported activity as an IRE1α inhibitor useful for unfolded protein response research.
- Stable when stored at recommended temperatures for powder and solutions.
- Molecular formula C8H7BrO3 and molecular weight 231.04 aid experimental planning.
Medchemexpress LLC 4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid hydrochloride | 2829282-00-8 | MFCD02262124 | 99.4% | 245.66 g/mol | C10H12ClNO4 | 1 ML
LY367385 hydrochloride is a selective mGluR1a antagonist supplied as a hydrochloride salt for research use. It is available as a solid and as a ready-to-use 10 mM solution in DMSO (1 mL vial), suitable for in vitro pharmacology and biochemical assays.
- High purity (99.4%) for reproducible assay results.
- Available as 10 mM solution in DMSO for convenient dosing.
- Also supplied as solid for custom formulation and storage.
- Molecular weight 245.66 g/mol and formula C10H12ClNO4.
- CAS number 2829282-00-8 for unambiguous substance identification.
Apexbio Technology LLC EZ Cap Mouse IL-23 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-23 mRNA (Interleukin-23) encodes IL-12 cytokine It consists of two subunits IL-23 p19 and IL-12 p40 IL-23 binds to its specific receptor IL-23R activating downstream signaling pathways including the JAK-STAT pathway thus promoting inflammatory responses IL-23 is a potential therapeutic target for various diseases including psoriasis Crohn s disease and multiple sclerosis In recent years biological agents targeting IL-23 such as monoclonal antibodies have been developed for clinical application showing good efficacy and safety EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse GM-CSF mRNA (m1Ψ) 100ug (1mg/mL)
GM-CSF mRNA encodes Granulocyte-Macrophage Colony-Stimulating Factor (CSF) produced by T cells macrophages endothelial cells and fibroblasts It stimulates the differentiation of hematopoietic stem cells in bone marrow into granulocytes and macrophages thereby enhancing the body s immune response capability GM-CSF not only promotes leukocyte production but also enhances their functions such as improving phagocytosis and antigen presentation abilities Clinically GM-CSF is used to treat certain types of leukopenia and serves as an adjuvant in cancer immunotherapy EZ Cap Mouse GM-CSF mRNA (m1 ) is provided at 1 mg/mL It expresses mouse-derived GM-CSF cytokine It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo