Phenols
Medchemexpress LLC Serpin A3N Mouse P 50ug
Recombinant mouse Serpin A3N is a purified, His-tagged serine protease inhibitor expressed in Pichia pastoris for research applications. This reagent is intended for biochemical characterization, antibody development, and cell-based assays; it is supplied in a 50 μg pack with reported purity of ~92% and a molecular weight of ~46.8 kDa.
- Suitable for biochemical assays and functional studies.
- Useful for antibody generation and validation.
- Expressed in Pichia pastoris for eukaryotic processing.
- Includes N-terminal 6xHis tag for affinity purification or detection.
- High reported purity (~92%) and defined molecular weight (~46.8 kDa).
- Small pack size (50 μg) for pilot experiments and method development.
Medchemexpress LLC GM-CSF Rhesus macaq 10ug
Recombinant GM-CSF protein derived from rhesus macaque, provided lyophilized for research use. The protein stimulates granulocyte and monocyte lineage cells and is intended for in vitro applications including cell culture, immune cell stimulation, and assay development. Expressed in E. coli and characterized for purity and molecular mass.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Predicted molecular mass of approximately 14 kDa.
- Lyophilized formulation for convenient storage and reconstitution.
- Suitable for in vitro cell culture and immune stimulation assays.
- Stable when aliquoted and stored at -20°C or -80°C for extended periods.
Medchemexpress LLC Guadecitabine sodium | 929904-85-8 | C18H23N9NaO10P | 1 ML
Guadecitabine sodium is a second-generation DNA methyltransferases (DNMT) inhibitor for research of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). It is for research use only and not sold to patients.
- Second-generation DNA methyltransferases (DNMT) inhibitor
- Induces dose-dependent increase in p16 expression
- Inhibits DNA methylation
- Effective in reducing DNA methylation and retarding tumor growth in vivo
- Reactivates p16 gene expression
- Better tolerated in vivo than 5-Aza-CdR
- Involved in numerous clinical trials for various conditions
Medchemexpress LLC Rhosin hydrochloride | 1281870-42-5 | 99.94% | 394.86 | 1 ML
Rhosin hydrochloride is a potent and specific inhibitor of the RhoA subfamily Rho GTPases. It works by binding to RhoA, inhibiting its interaction with GEF proteins. This compound does not interact with Cdc42, Rac1, or LARG. It promotes stress resiliency and induces cell apoptosis, making it suitable for various research applications.
- Specifically inhibits RhoA subfamily Rho GTPases
- Induces cell apoptosis
- Promotes stress resiliency by enhancing D1-MSN plasticity
- Reduces hyperexcitability
- Does not interact with Cdc42, Rac1, or LARG
Sigma Aldrich Fine Chemicals Biosciences p-Cresol >=99%, FG | 106-44-5 | MFCD00002376 | 10KG
p-Cresol >=99%, FG | Purity: >=99% | Mol Wt: 108.14 | 106-44-5 | MFCD00002376 | 10KG
Medchemexpress LLC Rs 17053 hydrochloride | 169505-93-5 | MFCD09971032 | 99.9% | 449.41 | C24H30Cl2N2O2 | 50 MG
RS 17053 hydrochloride is a research-grade small molecule that functions as a potent, selective α1A adrenoceptor antagonist for pharmacological studies. Supplied as a solid with high purity, it includes manufacturer-specified solubility, formulation, and storage guidance for both in vitro and in vivo use.
- Potent, selective α1A adrenoceptor antagonist (pKi 9.1; pA2 9.8).
- High purity: 99.9%.
- Solid form, white to off-white.
- Soluble in DMSO (~100 mg/mL); ultrasonic assistance recommended.
- Compatible with multiple in vivo formulations at ≥2.08 mg/mL for clear solutions.
- Stable with recommended storage: sealed at 4°C; in solution -80°C for long-term.
Apexbio Technology LLC AZD-3463 1356962-20-3 100mg
AZD-3463 (CAS 1356962-20-3) is an orally bioavailable small molecule inhibitor targeting anaplastic lymphoma kinase (ALK) and insulin-like growth factor 1 receptor (IGF1R) exhibiting a Ki of 0 75 nM ALK expression is predominantly neuronal and is upregulated in neuroblastoma where its activation promotes cell survival and proliferation In vitro AZD-3463 suppresses proliferation of neuroblastoma cell lines with wild-type or mutant ALK by inhibiting the ALK-mediated PI3K/AKT/mTOR signaling pathway leading to apoptosis and autophagy induction AZD-3463 also enhances the cytotoxicity of chemotherapeutic agents such as doxorubicin and temozolomide In vivo it has demonstrated efficacy in reducing neuroblastoma growth in xenograft mouse models
Apexbio Technology LLC Chlorhexidine HCl 3697-42-5 10mM (in 1mL DMSO)
Chlorhexidine HCl (CAS 3697-42-5) is an antiseptic agent designed to interact with microbial cell membranes thereby increasing membrane permeability and disrupting membrane integrity Chlorhexidine HCl exerts its biological activity primarily through binding to negatively charged surfaces of bacterial membranes resulting in leakage of cellular contents and consequent microbial cell death In microbiological assays chlorhexidine HCl demonstrates broad-spectrum antimicrobial activity with reported IC50 values against various microbial strains generally in the micromolar concentration range though specific values depend on the target organism and experimental conditions Based on these pharmacological properties chlorhexidine HCl holds research potential in antimicrobial susceptibility testing and as a control compound in comparative studies of novel antimicrobial agents
Medchemexpress LLC MELK-8a hydrochloride | 2096992-20-8 | 99.3% | 469.02 g/mol | C25H33ClN6O | 25 MG
MELK-8a hydrochloride is a potent small-molecule inhibitor of maternal embryonic leucine zipper kinase (MELK) with a reported IC50 of 2 nM. Supplied as the hydrochloride salt with high chemical purity, it is intended for research use in biochemical and cellular studies targeting MELK-dependent pathways.
- Potent MELK inhibition with an IC50 of 2 nM.
- Hydrochloride salt for improved stability and handling.
- High purity suitable for biochemical and cellular assays.
- Molecular weight 469.02 g/mol and formula C25H33ClN6O.
- Soluble in DMSO; solution formats available for convenient dosing.
- Intended for research use only; not for human or diagnostic use.
Apexbio Technology LLC Olopatadine HCl 140462-76-6 10mM (in 1mL DMSO)
Olopatadine HCl (CAS 140462-76-6) is a small molecule antagonist of the histamine H1 receptor classified as a second-generation antihistamine By selectively blocking H1 receptors olopatadine inhibits histamine-mediated inflammatory responses in target tissues Preclinical studies have shown that olopatadine suppresses allergic manifestations such as ear swelling indicating its potential to modulate acute hypersensitivity reactions This compound is widely utilized in research focused on the mechanisms of allergic conjunctivitis and other histamine-dependent allergic disorders
Medchemexpress LLC O-(6-chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium (hexafluorophosphate) | 330645-87-9 | 99.5% | 413.69 | 100 G
HCTU, chemically known as O-(6-chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, is a biochemical reagent primarily used as a biological material or organic compound for life science related research.
- Used as a biochemical reagent
- Functions as a biological material or organic compound
- Suitable for life science related research
- Appears as a white to off-white solid
- High purity (over 99%)
Medchemexpress LLC Nsc23005 sodium | 1796596-46-7 | MFCD30534395 | 99.5% | 305.33 g/mol | C13H16NNaO4S | 1 ML
NSC23005 sodium is a small-molecule p18 inhibitor used in research to promote hematopoietic stem cell (HSC) expansion in murine and human systems. It is supplied as a 10 mM solution in DMSO or as a solid and is characterized by high purity and defined storage recommendations for laboratory use.
- Promotes hematopoietic stem cell expansion in murine and human models.
- Potent p18 inhibition with reported ED50 of 5.21 nM.
- High purity (99.52%) suitable for research applications.
- Available as a 10 mM solution in DMSO and in solid milligram quantities.
- Store sealed at 4°C; in solvent store at -80°C up to 6 months or -20°C up to 1 month.
Medchemexpress LLC Cephapirin (sodium) | 24356-60-3 | 95.7% | C17H16N3NaO6S2 | 1 ML
Cephapirin sodium is an ephalosporin antibiotic known for its broad-spectrum antimicrobial activity. It is effective against various bacterial strains, including Staphylococcus aureus, S. epidermidis, S. viridans, S. pyogenes, and Diplococcus pneumonia.
- Appearance: White to off-white solid
- Purity: 95.74%
- Molecular weight: 445.45
- Solubility in water: ≥ 100 mg/mL (224.49 mM)
- Solubility in DMSO: 33.33 mg/mL (74.82 mM)
- Effective against Staphylococcus aureus in vivo