Tropisetron Hydrochloride is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChR receptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. It possesses anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. It also reduces Ab-induced hippocampal neuroinflammation.
- Neuroprotective agent
- 5-HT3 receptor antagonist
- Calmodulin inhibitor
- Α7-nAChR receptor agonist
- Anti-inflammatory properties
- Immune-regulating functions
- Alleviates symptoms associated with chemotherapy and post-surgery
- Reduces Ab-induced hippocampal neuroinflammation