Phenols
Cambridge Isotope Laboratories US EPA Method 8276 Toxaphene Injection Internal Standard (13C10 99%) in nonane 1 2 mL
US EPA Method 8276 Toxaphene Injection Internal Standard (13C10 99%) in nonane 1 2 mL
Cambridge Isotope Laboratories Method 521 Nitrosamine Surrogate Mixture (D 98%) 100 ug/mL in methylene chloride-D2 1 2 mL
Method 521 Nitrosamine Surrogate Mixture (D 98%) 100 ug/mL in methylene chloride-D2 1 2 mL
Medchemexpress LLC MTR-106 | 1639357-93-9 | 99.4% | 525.62 | 5 MG
MTR-106 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor. It induces apoptosis and inhibits cell growth, making it suitable for cancer research.
- Potent and orally active G-quadruplex stabilizer
- RNA polymerase I inhibitor
- Induces apoptosis and inhibits cell growth
- Has antitumor activity in both HR-deficient cells and PARPi-resistant cells
- Induces cell cycle arrest and DNA damage
- Suppresses tumor growth in BRCA-deficient and PARPi-resistant xenografts in nude mice
Medchemexpress LLC Etamicastat hydrochloride | 677773-32-9 | 98.14% | 347.81 | 1 ML
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor with an IC50 value of 107 nM. It can be utilized in research pertaining to cardiovascular diseases.
- Potent and reversible dopamine-β-hydroxylase (DBH) inhibitor
- IC50 value of 107 nM
- Useful in cardiovascular disease research
- Supplied as 10 mM solution in DMSO
- Storage: Solid at 4°C under nitrogen; In solvent, -80°C for 6 months or -20°C for 1 month under nitrogen.
Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 25 MG
CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts. It induces apoptosis and differentiation, and demonstrates promising anti-leukemic effects. It is intended for research use only.
- Binds IGF2BP2
- Inhibits interaction with m6A-modified target transcripts
- Induces apoptosis
- Induces differentiation
- Demonstrates anti-leukemic effects
- For research use only
Medchemexpress LLC 3-Hydroxybenzoic acid | 99-06-9 | 138.12 | 1 ML
3-Hydroxybenzoic acid is an orally active endogenous metabolite. It acts as an agonist for GPR81 and GPR109A and functions as a stress response desensitizer. It can be utilized for anti-inflammatory and analgesic studies.
- Endogenous metabolite
- Agonist for GPR81 and GPR109A
- Stress response desensitizer
- Potential for anti-inflammatory and analgesic studies
- Orally active
Medchemexpress LLC 3-Hydroxybenzoic acid | 99-06-9 | 138.12 | 1 G
3-Hydroxybenzoic acid (Standard) is the analytical standard of 3-Hydroxybenzoic acid, intended for research and analytical applications.
- An orally active endogenous metabolite
- Agonist for GPR81 and GPR109A
- Acts as stress response desensitizer
- Can be used for anti-inflammatory and analgesic study
Medchemexpress LLC 1-Indanone (α-Hydrindone) | 83-33-0 | 132.16 | 25 G
1-Indanone is a biochemical reagent that can be utilized as a biological material or organic compound for life science-related research. It is an oxidation product and a component found in fuels, solvents, and varnishes. Additionally, it plays a role in steroid hormone biosynthesis and arachidonic acid metabolism pathways.
- Used as a biochemical reagent for life science research
- Functions as a biological material or organic compound
- Acts as an oxidation product
- A component in fuels, solvents, and varnishes
- Involved in steroid hormone biosynthesis and arachidonic acid metabolism pathways
Apexbio Technology LLC Xylometazoline HCl 1218-35-5 10mM (in 1mL DMSO)
Xylometazoline hydrochloride (CAS 1218-35-5) is a small molecule -adrenoceptor agonist with pronounced activity at the B-adrenoceptor subtype demonstrating an EC of 99 M Through stimulation of -adrenergic receptors it induces vasoconstriction of nasal mucosal blood vessels which forms the basis for its use as a nasal decongestant Xylometazoline HCl is utilized in biomedical research to investigate -adrenergic receptor signaling pathways and vascular response mechanisms as well as to model sympathomimetic drug action in preclinical studies
Medchemexpress LLC LV-320 | 2449093-46-1 | 95.0% | 520.11 | 1 ML
LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC50 of 24.5 μM and a Kd of 16 μM. It inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic, and active in vivo.
- Increases endogenous LC3B-II and protein p62 levels in SKBR3, MCF7, JIMT1, and MDA-MB-231 cells in a dose-dependent manner.
- Blocks autophagic flux in MDA-MB-231 cells.
- Achieves terminal blood levels of 169 μM and liver levels of 104 μM in GFP-LC3 mice following oral gavage.
- Significantly increases the accumulation of GFP-LC3 puncta and LC3B-II protein in treated animals without causing significant toxicity at tested doses.