Carboxylic acids and derivatives
Medchemexpress LLC m-PEG8-CH2COOH | 102013-72-9 | 99.9% | 5 G
m-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It has a molecular weight of 442.50 and a chemical formula of C19H38O11. This compound appears as a colorless to light yellow liquid with a density of 1.122 g/cm3. For in vitro solubility, it dissolves in DMSO at 200 mg/mL.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Molecular weight: 442.50
- Formula: C19H38O11
- Appearance: liquid
- Color: colorless to light yellow
- In vitro solubility: 200 mg/mL in DMSO
- Pure form storage: stable for 3 years at -20°C or 2 years at 4°C
- In solvent storage: stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 500 MG
Sodium lauroyl glutamate is an anionic amino acid surfactant primarily used in cleaning products. While it has the potential for irritant contact dermatitis, it also exhibits possible anti-irritating properties in surfactant mixtures on human skin. A 1% w/w solution demonstrates low irritation and has a pH value of 5.41.
- Anionic amino acid surfactant
- Mild surfactant
- Used mainly in cleaning products
- Exhibits possible anti-irritating potential in surfactant mixtures
- Low irritation to nude mouse skin at 1% w/w solution
- 1% w/w solution has a pH value of 5.41
- Appears as a white to off-white solid
eMolecules 4249-19-8 | (S)-3-Amino-2-methylpropanoic acid | MFCD07372875 | 250mg
Ambeed | tert-Butyldiphenylsilanol | 1g | 721418446 | A1524304 | 93547-88-7 | 256.420 | C16H20OSi
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Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 | C8H12O4 | 1g
Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
Chem-Impex International, Inc. Sodium citrate dihydrate | 6132-04-3 | MFCD00150031 | 2.5KG
Sodium citrate dihydrate, 6132-04-3, MFCD00150031, 2.5KG
Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 g/mol | C8H12O4 | 500mg
Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 50 MG
BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor. It demonstrates high affinity binding to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) and exhibits potent anti-cancer activity.
- Orally active, selective BET bromodomain inhibitor
- IC50 of 2.6 nM for BRD4
- Binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities
- Exhibits potent anti-cancer activity
- Induces G1-phase cell cycle arrest
- Inhibits c-Myc expression and upregulates p21 levels
- Reduces c-Myc, BCL-2, and CDK6 expressions
- Highly selective for BET bromodomain family (~1500-fold over EP300)
- Strong antitumor activities in MV4-11 mouse xenograft model
Advanced Chemblocks Inc ETHYL 3-(5-AMINOPYRIDIN-3-1G
Ethyl 3-(5-aminopyridin-3-yl)propanoate, 1G, CAS# 1260824-37-0, MFCD16036532, PURTIY: 95%
Accela Chembio Inc 2 | 4-thiazolidinedione | 100g | 2295-31-0 | MFCD00005478 | 97+% | Shelf Life: 1440 Days | Light Sensitive
2 | 4-thiazolidinedione | 100g | 2295-31-0 | MFCD00005478 | 97+% | Shelf Life: 1440 Days | Light Sensitive
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | MFCD00274131 | 98.1% | 379.96 g·mol⁻¹ | C19H38ClNO4 | 5 MG
Lauroyl-L-carnitine chloride is an acylcarnitine-derived absorption enhancer used in research to increase the oral bioavailability of peptide compounds. It is provided as a high-purity solid for laboratory use and can be prepared as solutions for experimental assays following recommended storage conditions.
- Orally active absorption enhancer for peptide compounds.
- Improves oral bioavailability of peptide therapeutics in preclinical studies.
- Supplied as a high-purity solid suitable for solution preparation.
- Available in small research pack sizes and larger quantities on request.
- Stable when stored sealed at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
- Molecular formula C19H38ClNO4; molecular weight 379.96 g·mol⁻¹.