Carboxylic acids and derivatives
Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.79% | 804.93 | 10 MG
VTP50469 fumarate | 2169919-29-1 | 99.79% | 804.93 | 10 MG
Selleck Chemical LLC Fumonisin B1
Fumonisin B1 is a mycotoxin produced by Fusarium moniliforme Sheldon and a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) an enzyme vital for the de novo synthesis of sphingolipids It exhibits an IC50 of 0 1 M for N-acyltransferase (ceramide synthase) in rat liver microsomes and also reduces the conversion of [3H]sphingosine to [3H]ceramide in intact hepatocytes
Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 99.9% | 541.58 | 5 MG
Filgotinib maleate is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It effectively inhibits JAK1, JAK2, JAK3, and TYK2. It also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. It can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
- Inhibits differentiation of Th2 cells and Th1 cells.
- Produces dose-dependent bone damage protection.
- Prevents the development of inflammation in animal models of collagen-induced arthritis.
- Reduces inflammatory cell infiltration.
- Protects articular cartilage and bone.
- Reduces serum levels of inflammatory cytokines and chemokines.
Medchemexpress LLC GlyH-101 | 328541-79-3 | 99.7% | 493.15 | 5 MG
GlyH-101 is a potent inhibitor of CFTR (Cystic Fibrosis Transmembrane conductance Regulator) and VSORC (Volume-Sensitive Outwardly Rectifying Chloride) conductance. It exhibits antiproliferative activity by inhibiting CFTR-like and VSORC currents and is intended for research use only.
- Potent CFTR inhibitor
- Potent and reversible VSORC inhibitor
- Exhibits antiproliferative activity in PCT and PS120 cells
- Inhibits CFTR-like current in PCT cells
- Inhibits VSORC current in PS120 and PCT cells
- Reduces cholera toxin-induced intestinal fluid secretion in mice
- Available as a solid, light yellow to yellow
- Soluble in DMSO
eMolecules 6097-08-1 | N-(5-Hexynyl)phthalimide | MFCD00671372 | 25g
Combi-Blocks | N-(5-Hexynyl)phthalimide | 25g | 537621690 | QF-9870 | 98.000 | 6097-08-1 | MFCD00671372 | 227.263 | C14H13NO2
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![eMolecules 543910-82-3 | CIS-4-OXO-OCTAHYDRO-ISOINDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER | AstaTech478.630 | C26H42N2O6 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2CCCC(=O)[C@H]2C1.CC(C)(C)OC(=O)N1C[C@@H]2CCCC(=O)[C@@H]2C1 | 0.25g | 449790337](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502172195.JPG-250.jpg)
eMolecules 543910-82-3 | CIS-4-OXO-OCTAHYDRO-ISOINDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER | AstaTech478.630 | C26H42N2O6 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2CCCC(=O)[C@H]2C1.CC(C)(C)OC(=O)N1C[C@@H]2CCCC(=O)[C@@H]2C1 | 0.25g | 449790337
CIS-4-OXO-OCTAHYDRO-ISOINDOLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER | AstaTech | 543910-82-3478.630 | C26H42N2O6 | 95.000 | CC(C)(C)OC(=O)N1C[C@H]2CCCC(=O)[C@H]2C1.CC(C)(C)OC(=O)N1C[C@@H]2CCCC(=O)[C@@H]2C1 | 0.25g | 449790337
eMolecules 2-Picolinyl hydrazide | Combi-Blocks | 1452-63-7 | MFCD00059782 | 137.142 | C6H7N3O | 98.000 | NNC(=O)c1ccccn1 | 5g | 267198271
2-Picolinyl hydrazide | Combi-Blocks | 1452-63-7 | MFCD00059782 | 137.142 | C6H7N3O | 98.000 | NNC(=O)c1ccccn1 | 5g | 267198271
eMolecules 540-69-2 | Ammonium formate | Oakwood Chemicals | MFCD00013103 | 63.056 | CH5NO2 | 97.000 | N.OC=O | 25g | 480144574
Ammonium formate | Oakwood Chemicals | 540-69-2 | MFCD00013103 | 63.056 | CH5NO2 | 97.000 | N.OC=O | 25g | 480144574
Medchemexpress LLC ODN 1585 (sodium) | DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 1 MG
ODN 1585 (sodium) is a potent inducer of IFN and TNFα production, and a strong stimulator of NK (natural killer) cell function. It increases CD8+ T-cell function, including IFN-γ production. This product has been shown to induce regression of established melanomas and offer complete protection against malaria in mice. It can be used for acute myelogenous leukemia (AML) and malaria research, and also serves as a vaccine adjuvant.
- Potent inducer of IFN and TNFα production
- Strong stimulator of natural killer (NK) cell function
- Increases CD8+ T-cell function and IFN-γ production
- Induces regression of established melanomas
- Confers protection against malaria
- Applicable for acute myelogenous leukemia (AML) and malaria research
- Functions as a vaccine adjuvant
- Induces PBMC to produce IFN-α
- Stimulates NK cell-mediated lysis of K562 cells
Medchemexpress LLC 2-Bromoacetamide | 683-57-8 | 137.96 | 25 G
2-Bromoacetamide is a disinfection byproduct known to inactivate liver alcohol dehydrogenase and interfere with microtubule and actin cytoskeletal function. It is also a potent developmental toxicant in animals.
- Inactivates liver alcohol dehydrogenase.
- Reduces egg cylinder formation rate and disrupts cell lineage differentiation in mouse embryos.
- Reduces first polar body extrusion rate and disrupts spindle structure in mouse and human oocytes.
- Interferes with microtubule and actin cytoskeleton functions.