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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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FM-381 is a potent covalent reversible inhibitor of Janus kinase 3 (JAK3) that targets the unique Cys909 residue. It demonstrates sub-nanomolar potency and strong selectivity versus other JAK family members, and is supplied as a high-purity research reagent for biochemical and cellular studies.
Potent JAK3 inhibition (IC50 127 pM)
High selectivity over JAK1, JAK2, and TYK2
High purity suitable for research applications
Stable powder storage at -20°C for long-term use
Soluble in DMSO (8.33 mg/mL) for in vitro assays
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More