Carboxylic acids and derivatives
Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | 98.5% | 649.70 | 5 MG
Vicriviroc maleate is a potent, selective, and orally bioavailable CCR5 antagonist. It inhibits HIV-1 in PBMC cells and demonstrates good oral availability in rats and monkeys, making it suitable for various research applications.
- Potent, selective, and orally bioavailable CCR5 antagonist with a Ki of 2.5 nM
- Inhibits HIV-1 in PBMC cells with IC90s ranging from 1.8 nM to 10 nM
- Exhibits good oral availability in rats and monkeys (10 mg/kg)
- Weak activity against hERG (IC50, 5.8 μM)
- Suppresses RANTES-induced signaling with a mean IC50 of 4.2 ± 1.3 nM
- Potently suppresses various viral isolates with geometric mean EC50s of 0.04-2.3 nM and IC90s of 0.45-18 nM
eMolecules 6515-13-5 | 2-(1-Propen-2-yl)pyridine | Accela ChemBio (ASD) | MFCD18384263 | 119.167 | C8H9N | 97.000 | CC(=C)c1ccccn1 | 1g | 375967381
2-(1-Propen-2-yl)pyridine | Accela ChemBio (ASD) | 6515-13-5 | MFCD18384263 | 119.167 | C8H9N | 97.000 | CC(=C)c1ccccn1 | 1g | 375967381
Advanced Chemblocks Inc CIS-METHYL 3-HYDROXY-1-METHY1G
CIS-METHYL 3-HYDROXY-1-METHYL-CYCLOBUTANECARBOXYLATE | Purity: 97% | 626238-08-2 | MFCD23105987 | 1G
![Medchemexpress LLC 6-[2-(2,4-difluorophenoxy)-5-(ethylsulfonylmethyl)-3-pyridinyl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-on | 2411226-02-1 | 99.9% | 459.47 g·mol⁻¹ | C22H19F2N3O4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262234.png-250.jpg)
Medchemexpress LLC 6-[2-(2,4-difluorophenoxy)-5-(ethylsulfonylmethyl)-3-pyridinyl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-on | 2411226-02-1 | 99.9% | 459.47 g·mol⁻¹ | C22H19F2N3O4S | 5 MG
BET bromodomain inhibitor 1 is a selective, orally active inhibitor of bromodomain and extra-terminal (BET) proteins with potent activity against BRD4 (IC50 = 2.6 nM). Supplied as a white to off-white solid with high purity, it is used in epigenetic target validation and anticancer mechanism research.
- Potent BRD4 inhibition (IC50 2.6 nM).
- Low-nanomolar binding to BET family bromodomains.
- High purity suitable for research (99.9%).
- Soluble in DMSO at 100 mg/mL with warming and sonication.
- Stable when stored as a powder at -20°C for long-term storage.
eMolecules 197855-65-5 | Z-FA-FMK | MFCD02684535 | 10mg
Ambeed | 3-Amino-2-bromo-5-methylpyridine | 1g | 506390463 | A345410 | 34552-14-2 | MFCD08277281 | 187.040 | C6H7BrN2
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Medchemexpress LLC Monomethylauristatin F | 745017-94-1 | MFCD25976742 | >95.0% | 731.96 g/mol | C39H65N5O8 | 50 MG
MMAF (Monomethylauristatin F) is a synthetic antimitotic agent that inhibits tubulin polymerization and is widely used as a cytotoxic payload in antibody-drug conjugates (ADCs) and for antitumor research. It is supplied for research use and should be handled under appropriate safety precautions.
- Potent tubulin polymerization inhibitor.
- Used as a cytotoxic payload in antibody-drug conjugates (ADCs).
- Cas number 745017-94-1.
- Molecular formula C39H65N5O8; molecular weight 731.96 g/mol.
- Typical storage: 4°C, sealed and protected from moisture.
- Common research pack size: 50 mg.
eMolecules 41204-08-4 | A-BRMO-3,4-DICHLOROPHENYLACETIC ACID ETHYL ESTER | AstaTech | MFCD04116366 | 311.980 | C10H9BrCl2O2 | 95.000 | CCOC(=O)C(Br)c1ccc(Cl)c(Cl)c1 | 5g | 397208736
A-BRMO-3,4-DICHLOROPHENYLACETIC ACID ETHYL ESTER | AstaTech | 41204-08-4 | MFCD04116366 | 311.980 | C10H9BrCl2O2 | 95.000 | CCOC(=O)C(Br)c1ccc(Cl)c(Cl)c1 | 5g | 397208736
eMolecules 493-52-7 | Methyl Red free acid | Chem-Impex269.304 | C15H15N3O2 | 0.000 | CN(C)c1ccc(cc1)N=Nc1ccccc1C(O)=O | 25g | 369602256
Methyl Red free acid | Chem-Impex | 493-52-7269.304 | C15H15N3O2 | 0.000 | CN(C)c1ccc(cc1)N=Nc1ccccc1C(O)=O | 25g | 369602256
Medchemexpress LLC HY-13229 5mg Medchemexpress, BOC-D-FMK CAS:634911-80-1 Purity:>98%
Medchemexpress, HY-13229 5mg BOC-D-FMK CAS:634911-80-1 Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor. Boc-D-FMK inhibits apoptosis stimulated by TNF-α with an IC50 of 39 µM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-112430 10mg Medchemexpress, TRPM8 antagonist 2 CAS:259674-19-6 Purity:>98%
Medchemexpress, HY-112430 10mg TRPM8 antagonist 2 CAS:259674-19-6 TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC CA 074 134448-10-5 10mg
CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations