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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
CA-170 is a small-molecule dual inhibitor of the immune checkpoints VISTA and PD-L1 developed for preclinical research. It modulates T-cell proliferation and effector functions suppressed by PD-L1/L2 and VISTA, and is used to study immune checkpoint pathways in vitro and in vivo.
Dual inhibitor of VISTA and PD-L1
Orally active small-molecule suitable for preclinical studies
Modulates T-cell proliferation and effector functions
Defined chemical properties to support reproducibility
Storage recommendations provided for powder and solutions
Intended for research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
SRT 1460 is a small-molecule activator of SIRT1 provided for research use in biochemical and cell-based studies. It activates SIRT1 with an EC1.5 of 2.9 μM, shows strong selectivity versus SIRT2 and SIRT3 (EC1.5 > 300 μM), and is supplied as an off-white to light yellow solid with solubility ≈10 mg/mL in DMSO.
Potent SIRT1 activation (EC1.5 = 2.9 μM).
High selectivity versus SIRT2 and SIRT3 (EC1.5 > 300 μM).
Off-white to light yellow solid appearance.
Soluble in DMSO for convenient stock preparation (≈10 mg/mL).
Stable when stored frozen as powder for extended periods.
Suitable for biochemical and cell-based assays.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More