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Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
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diABZI-C2-NH2 is an active analogue containing a primary amine functionality and acts as a STING agonist. It has shown strong anti-tumor activity in immunocompetent mice with syngeneic colon tumors, leading to complete and lasting regression of tumors. This compound can be covalently immobilized on sepharose beads for affinity-capture of potential target proteins from THP1 cell lysate.
Functions as a STING agonist
Exhibits strong anti-tumor activity in immunocompetent mice
Leads to complete and lasting regression of tumors
Can be covalently immobilized on sepharose beads
Useful for affinity-capture of potential target proteins from THP1 cell lysate
Enhanced binding to STING and cellular function
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
diABZI-C2-NH2 is a synthetic small-molecule STING agonist for research use. It is an active analogue containing a primary amine functionality and is supplied with supporting documentation (data sheet, COA, SDS) for experimental reproducibility.
Acts as a STING agonist in immuno-oncology research
Contains a primary amine functionality
High purity: 96.1%
Available as solid and as a 10 mM solution in DMSO
Soluble in DMSO (100 mg/mL) for in vitro use
Recommended storage: solid at -20°C under nitrogen; in solution store at -80°C
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More