SRT 1460 is a potent, selective activator of Sirtuin-1 (SIRT1) commonly used in research to study sirtuin signaling, metabolism, and aging pathways. It has an EC1.5 of 2.9 μM for SIRT1, shows strong selectivity versus SIRT2 and SIRT3, and demonstrates greater potency than resveratrol.
- Potent SIRT1 activation with EC1.5 = 2.9 μM.
- High selectivity versus SIRT2 and SIRT3 (EC1.5 > 300 μM).
- Greater potency than resveratrol in sirtuin assays.
- Available as solid and as 10 mM solution in DMSO for convenience.
- High purity (≈98.2%) suitable for in vitro studies.
- Storage recommendations for powder and in solvent to preserve stability.
- Intended for research use only and not for human or clinical use.