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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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SNX-0723 is a small-molecule Hsp90 inhibitor used in research to investigate Hsp90 biology and anti-plasmodial activity. It is supplied as a solid for in vitro and in vivo applications.
Potent Hsp90 inhibitor active against human and Plasmodium Hsp90.
High purity (≈99.1%).
Molecular weight 399.46 g/mol; formula C22H26FN3O3.
Off-white to light yellow solid; supplied in 10 mg amount.
Soluble in DMSO (~20.83 mg/mL); in vivo formulation protocols available.
Powder storage: -20°C for long-term stability; solution storage at -80°C recommended.
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2 6-Dihydroxyacetophenone a polyphenolic derivative of Acetophenone (HY-Y0989) is an orally active mTOR inhibitor 2 6-Dihydroxyacetophenone shows antioxidant activity 2 6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells 2 6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle induces apoptosis and suppresses cell migration in CRC cells 2 6-Dihydroxyacetophenone inhibits xanthine oxidase (XOD) with an IC50 of 1 24 mM 2 6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice reduces plasma cholesterol in hypercholesterolemic rats and inhibits lipid accumulation in HFD-induced obese mice 2 6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC) hyperuricemia and hypercholesterolemia[1][2][3][4][5][6]
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