Aminobenzoic acids and derivatives
Apexbio Technology LLC Eprosartan Mesylate 144143-96-4 50mg
Eprosartan Mesylate is a small-molecule antagonist targeting the angiotensin II AT1 receptor It is designed to selectively inhibit the AT1 receptor subtype thereby modulating vasoconstriction and aldosterone secretion mechanisms in cardiovascular systems Eprosartan Mesylate exerts its biological activity primarily through competitive binding to AT1 receptors interfering with angiotensin II action In studies using rat and human adrenal cortical membranes Eprosartan Mesylate demonstrates inhibitory activity with IC50 values of approximately 9 2 nM and 3 9 nM respectively Based on these pharmacological properties Eprosartan Mesylate holds research potential in angiotensin II-mediated signal transduction pathways hypertension models and related cardiovascular diseases
Chem-Impex International, Inc. 4-Amino-3-methylbenzoic acid | MFCD00007736 | 5G
4-Amino-3-methylbenzoic acid, MFCD00007736, 5G
Selleck Chemical LLC Withaferin A
Withaferin A (WFA) potently inhibits NF- B activation by preventing the tumor necrosis factor-induced activation of I B kinase via a thioalkylation-sensitive redox mechanism Withaferin A binds to the intermediate filament (IF) protein vimentin with antitumor and antiangiogenesis activity Withaferin A is a steroidal lactone isolated from Withania somnifera
Medchemexpress LLC PBT434 mesylate | 2387898-69-1 | 99.9% | 50 MG
PBT434 mesylate is the methanesulfonate salt of a small-molecule inhibitor of α-synuclein aggregation that demonstrates oral activity and crosses the blood-brain barrier, supplied for preclinical research. It also exhibits iron-modulating properties and is provided as a high-purity solid with defined storage conditions.
- High purity: 99.9%.
- Molecular weight 398.26 g·mol⁻1.
- Chemical formula C13H17Cl2N3O5S.
- Available in small pack sizes including 50 MG.
- Store sealed at 4°C; in solvent keep at -80°C up to 6 months, or -20°C up to 1 month.
- Intended for preclinical studies of protein aggregation and iron modulation; follow appropriate safety guidance.
Apexbio Technology LLC Licochalcone A 58749-22-7 20mg
Licochalcone A (CAS 58749-22-7) is a flavonoid compound isolated from the root of Glycyrrhiza species (licorice) It modulates multiple biological pathways including the inhibition of inflammatory mediators such as NF- B and the suppression of oxidative stress by regulating antioxidant enzymes Licochalcone A has demonstrated antiproliferative effects in various cell models impacting cell cycle progression and apoptosis Due to these properties it is widely utilized in studies related to inflammation cancer and oxidative stress-associated diseases The compound should be stored in a cool dry and sealed environment to maintain stability
