Aminobenzoic acids and derivatives
Cambridge Isotope Laboratories Modified JIS PCB Alt A Extended Calibration Solution (CS5H) 0 2 mL
Modified JIS PCB Alt A Extended Calibration Solution (CS5H) 0 2 mL
Chemscene 2-Amino-2-methyl-1-propanol | 25g | CS-W013743 | 5% Water 95% | 124-68-5 | MFCD00008051 | 89 14 | C4H11NO
Chemscene | 2-Amino-2-methyl-1-propanol | 25g | CS-W013743 | 5% Water 95% | 124-68-5 | MFCD00008051 | 89 14 | C4H11NO
Medchemexpress LLC A-395 hydrochloride | 2089148-72-9 | MFCD31563589 | 98.4% | 486.65 g·mol⁻1 | C26H35FN4O2S · xHCl | 1 ML
A-395 hydrochloride is a small-molecule chemical probe that antagonizes the EED subunit of the Polycomb repressive complex 2 (PRC2). It binds in the H3K27me3-binding pocket of EED, preventing allosteric activation of EZH2 and reducing H3K27 methylation; it shows potent inhibition of the PRC2 complex (reported IC50 ≈ 18 nM). The compound is supplied as the hydrochloride salt and is commonly used in biochemical and cellular studies.
- Potent EED antagonist with low-nanomolar PRC2 inhibition.
- Prevents allosteric activation of EZH2 and reduces H3K27 methylation.
- Validated in structural and biochemical studies for target engagement.
- Suitable as a chemical probe for studying PRC2 biology in cells and assays.
- Supplied as a hydrochloride salt with good solubility in DMSO.
- Available in solution formats for direct use in biochemical assays.
Selleck Chemical LLC A-803467 S2785-50mg
A-803467 is a selective NaV1 8 channel blocker with IC50 of 8 nM blocks tetrodotoxin-resistant currents exhibits 100-fold selectivity against human NaV1 2 NaV1 3 NaV1 5 and NaV1 7
Chemscene Hydroxyurea | 500g | CS-2353 | 98% | 127-07-1 | MFCD00007943 | 76 05 | CH4N2O2
Chemscene | Hydroxyurea | 500g | CS-2353 | 98% | 127-07-1 | MFCD00007943 | 76 05 | CH4N2O2
Chemscene 2-Bromo-3-fluoroaniline | 100g | CS-W003391 | 98% | 111721-75-6 | MFCD07369915 | 190 01 | C6H5BrFN
Chemscene | 2-Bromo-3-fluoroaniline | 100g | CS-W003391 | 98% | 111721-75-6 | MFCD07369915 | 190 01 | C6H5BrFN
Apexbio Technology LLC Safinamide Mesylate 202825-46-5 10mM (in 1mL DMSO)
Safinamide Mesylate (CAS 202825-46-5) is the mesylate salt form of safinamide a selective and reversible inhibitor of monoamine oxidase B (MAO-B) Safinamide exhibits an IC50 of 98 nM for MAO-B inhibition leading to enhanced dopaminergic transmission by reducing dopamine degradation In addition to MAO-B inhibition safinamide modulates sodium and calcium channels (IC50 8 2 M and 31 5 M respectively) and suppresses glutamate release ( 56 4 M) contributing to its anticonvulsant properties Research applications include the study of Parkinson s disease mechanisms and the investigation of dopaminergic and glutamatergic modulation
Chemscene (1S)-( )-(10-Camphorsulfonyl)oxaziridine | 25g | CS-W008074 | 98% | 104322-63-6 | MFCD00075319 | 229 30 | C10H15NO3S
Chemscene | (1S)-( )-(10-Camphorsulfonyl)oxaziridine | 25g | CS-W008074 | 98% | 104322-63-6 | MFCD00075319 | 229 30 | C10H15NO3S
Chemscene Adipic acid dihydrazide | 25g | CS-0010116 | 98% | 1071-93-8 | MFCD00007614 | 174 20 | C6H14N4O2
Chemscene | Adipic acid dihydrazide | 25g | CS-0010116 | 98% | 1071-93-8 | MFCD00007614 | 174 20 | C6H14N4O2
Chemscene 2-Bromo-5-iodobenzonitrile | 1g | CS-W008126 | 98% | 1252046-13-1 | MFCD09025663 | 307 92 | C7H3BrIN
Chemscene | 2-Bromo-5-iodobenzonitrile | 1g | CS-W008126 | 98% | 1252046-13-1 | MFCD09025663 | 307 92 | C7H3BrIN
Chemscene 3 4-Dihydroxybenzeneacetic acid | 10g | CS-W001080 | 98% | 102-32-9 | MFCD00004338 | 168 15 | C8H8O4
Chemscene | 3 4-Dihydroxybenzeneacetic acid | 10g | CS-W001080 | 98% | 102-32-9 | MFCD00004338 | 168 15 | C8H8O4