Benzenesulfonamides
eMolecules 701-34-8 | 4-BROMOBENZENESULFONAMIDE | AstaTech | MFCD00051977 | 236.080 | C6H6BrNO2S | 95.000 | NS(=O)(=O)c1ccc(Br)cc1 | 100g | 323616764
4-BROMOBENZENESULFONAMIDE | AstaTech | 701-34-8 | MFCD00051977 | 236.080 | C6H6BrNO2S | 95.000 | NS(=O)(=O)c1ccc(Br)cc1 | 100g | 323616764
![Medchemexpress LLC 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- | 2160546-07-4 | 100.0% | 377.27 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000364203-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- | 2160546-07-4 | 100.0% | 377.27 | 5 MG
IACS-13909 is a selective, potent, and orally active SHP2 allosteric inhibitor. It exhibits greater selectivity for SHP2 over other phosphatases, including SHP1. This compound demonstrates antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinase (RTK)-dependent cancers.
- Potently suppresses the proliferation of wild-type SHP2 and KYSE-520 cells.
- Suppresses pERK and pMEK levels in wild-type SHP2 and KYSE-520 cells.
- Inhibits the proliferation of parental cells and NCI-H1975 CS cells in a dose-dependent manner.
- Achieved 100% tumor growth inhibition (TGI) in mice studies.
- Functions as a selective SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM.
eMolecules 133745-75-2 | N-Fluorobenzenesulfonimide | Ambeed | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 10g | 490562797
N-Fluorobenzenesulfonimide | Ambeed | 133745-75-2 | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 10g | 490562797
eMolecules 835619-41-5 | Medchem Express | Indeglitazar | 5mg | 446264614 | HY-14817 | MFCD18633304 | 389.42 | C19H19NO6S
Medchem Express | Indeglitazar | 5mg | 446264614 | HY-14817 | 835619-41-5 | MFCD18633304 | 389.420 | C19H19NO6S
Medchemexpress LLC Racemate of OSMI-1 | 2748153-92-4 | 96.5% | 25MG
Racemate of OSMI-1 | 2748153-92-4 | 96.5% | 25MG
Medchemexpress LLC HY-A0013A 50mg Medchemexpress, Bosentan (hydrate) CAS:157212-55-0 Purity:>98%
Medchemexpress, HY-A0013A 50mg Bosentan (hydrate) CAS:157212-55-0 Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-108360 10mg Medchemexpress, PDD 00017273 CAS:1945950-21-9 Purity:>98%
Medchemexpress, HY-108360 10mg PDD 00017273 CAS:1945950-21-9 PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase ( PARG ), with an IC 50 of 26 nM, and a K D of 1.45 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-112292 5mg Medchemexpress, GW806742X CAS:579515-63-2 Purity:>98%
Medchemexpress, HY-112292 5mg GW806742X CAS:579515-63-2 GW806742X is a Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitor which binds the MLKL pseudokinase domain with a K d value of 9.3 μM and has anti-necroptosis activity. GW806742X has activity against VEGFR2 [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC PI3K-IN-1 (XL-147 derivative 1) | 1349796-36-6 | 99.9% | 100MG
PI3K-IN-1 (XL-147 derivative 1) | 1349796-36-6 | 99.9% | 100MG