Benzenesulfonamides
Medchemexpress LLC Pci-27483 | 871266-63-6 | 99.10% | 596.57 | 100 MG
Pci-27483 | 871266-63-6 | 99.10% | 596.57 | 100 MG
Selleck Chemical LLC Sildenafil Mesylate S4683-500mg
Sildenafil Mesylate(UK-92480 Mesylate) is a mesylate form of Sildenafil an inhibitor of Phosphodiesterase 5
Medchemexpress LLC GW806742X hydrochloride | 98.3% | 610.01 | 100 MG
GW806742X hydrochloride is an ATP mimetic and a potent inhibitor of MLKL (Mixed Lineage Kinase Domain-Like protein), binding to the MLKL pseudokinase domain with a Kd of 9.3 μM. It also exhibits activity against VEGFR2 with an IC50 of 2 nM. This compound has been shown to retard MLKL membrane translocation and inhibit necroptosis.
- Retards MLKL membrane translocation
- Inhibits necroptosis
- Inhibits necroptotic death of wild-type mouse dermal fibroblasts (MDFs) stimulated with TSQ in a dose-dependent manner
- Inhibits VEGF-induced proliferation of HUVECs with an IC50 of 5 nM
- Binds MLKL pseudokinase domain with a Kd of 9.3 μM
- Activity against VEGFR2 with an IC50 of 2 nM
eMolecules 326886-05-9 | Medchem Express | Shz-1 | 5mg | 785215131 | HY-108440 | MFCD00853265 | 355.21 | C13H11BrN2O3S
Ambeed | (R)-33-Bis[4-(trifluoromethyl)phenyl]-[11-binaphthalene]-22-diol | 100mg | 624120823 | A276989 | 791616-58-5 | 574.522 | C34H20F6O2
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Medchemexpress LLC Bosentan | 147536-97-8 | 99.9% | C27H29N5O6S | 1 ML
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors, with Ki values of 4.7 nM and 95 nM in human SMC, respectively. It is for research use only.
- Competitive and dual antagonist of endothelin-1 (ET)
- Acts on ETA and ETB receptors
- Research use only
![eMolecules 31696-45-4 | Ethyl 3-[(phenylsulfonyl)oxy]-5-isoxazoleacetate | Synthonix311.310 | C13H13NO6S | 97.000 | CCOC(=O)Cc1cc(OS(=O)(=O)c2ccccc2)no1 | 10mg | 786491789](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502456934.PNG-250.jpg)
eMolecules 31696-45-4 | Ethyl 3-[(phenylsulfonyl)oxy]-5-isoxazoleacetate | Synthonix311.310 | C13H13NO6S | 97.000 | CCOC(=O)Cc1cc(OS(=O)(=O)c2ccccc2)no1 | 10mg | 786491789
Ethyl 3-[(phenylsulfonyl)oxy]-5-isoxazoleacetate | Synthonix | 31696-45-4311.310 | C13H13NO6S | 97.000 | CCOC(=O)Cc1cc(OS(=O)(=O)c2ccccc2)no1 | 10mg | 786491789
eMolecules 402713-81-9 | Medchem Express | SB-399885 hydrochloride | 5mg | 446257985 | HY-103099 | MFCD09970355 | 482.8 | C18H22Cl3N3O4S
Medchem Express | BPU-11 | 5mg | 784543790 | HY-119102 | 909664-41-1 | 501.634 | C32H31N5O
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eMolecules 2271358-65-5 | Medchem Express | UAMC-3203 hydrochloride | 5mg | 455326080 | HY-112909A | 508.12 | C25H38ClN5O2S
Ambeed | 14-Bis(2-methyl-1H-imidazol-1-yl)butane | 100mg | 602852056 | A443716 | 52550-63-7 | 218.304 | C12H18N4
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eMolecules 73542-86-6 | 2-Cyanobenzenesulfonamide | Combi-Blocks | MFCD03094593 | 182.200 | C7H6N2O2S | 98.000 | NS(=O)(=O)c1ccccc1C#N | 25g | 439374605
2-Cyanobenzenesulfonamide | Combi-Blocks | 73542-86-6 | MFCD03094593 | 182.200 | C7H6N2O2S | 98.000 | NS(=O)(=O)c1ccccc1C#N | 25g | 439374605
Apexbio Technology LLC WAY 316606(Synonyms: WAY-316606, WAY316606, WAY 316606 sFRP-1 inhibitor, sFRP-1 inhibitor WAY 316606), 5mg, CAS: 915759-45-4.
WAY 316606 (CAS 915759-45-4) is a selective small molecule inhibitor targeting secreted frizzled-related protein 1 (sFRP-1) an endogenous antagonist of Wnt signaling WAY 316606 binds specifically to sFRP-1 (Kd 0 08 M) reducing its inhibitory effect and thus activating the canonical Wnt pathway In cell-based reporter assays using U2-OS osteosarcoma cells WAY 316606 dose-dependently promoted Wnt signaling with an EC50 of 0 65 M Ex vivo studies with neonatal murine calvarial tissue further demonstrated that WAY 316606 enhances osteoblast activity and bone formation This compound serves as a research tool for investigating Wnt-associated bone metabolism and therapeutic strategies for metabolic bone disorders
Medchemexpress LLC HY-10409 10mg Medchemexpress, Fedratinib CAS:936091-26-8 Purity:>98%
Medchemexpress, HY-10409 10mg Fedratinib CAS:936091-26-8 Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Methylenephosphonic acid CD73 inhibitor | 2216764-29-1 | 99.2% | 463.81 g·mol⁻¹ | C16H23ClN5O7P | 5 MG
CD73-IN-4 is a potent, selective methylenephosphonic acid inhibitor of ecto-5'-nucleotidase (CD73) with low-nanomolar activity against human CD73. It is supplied as a research reagent for biochemical and cell-based studies, with reported high purity and multiple pack size options. Molecular formula C16H23ClN5O7P; molecular weight 463.81 g·mol⁻¹.
eMolecules 1314594-23-4 | Medchem Express | PKR-IN-C51 | 5mg | 719835740 | HY-118131 | 367.456 | C23H21N5
Ambeed | 5-Chloro-2-cyano-3-methylpyridine | 1g | 525233235 | A681695 | 156072-84-3 | MFCD17214209 | 152.580 | C7H5ClN2
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