Sulfacetamide is a sulfonamide antibiotic with antifungal and antibacterial activities, commonly used in topical formulations for ophthalmic, dermatological, and hair solutions to treat bacterial infections, acne, and scalp conditions. It functions by targeting bacterial folic acid synthesis.
- Effective against both gram-positive and gram-negative bacteria
- Inhibits the synthesis of dihydro-folic acid and para-aminobenzoic acid
- Can be utilized for the study of ocular infections
- Acts as an antifungal drug through a CYP51A1-independent mechanism