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QL-X-138 is a small-molecule BTK/MNK dual kinase inhibitor that covalently binds to BTK and non-covalently to MNK. It is provided as a high-purity solid for laboratory research and has been characterized in preclinical studies for activity against hematologic malignancies and dengue virus.
Dual inhibition of Bruton tyrosine kinase (BTK) and MAPK-interacting kinase (MNK).
Covalent binding to BTK and non-covalent binding to MNK.
High-purity solid form suitable for laboratory research.
Molecular formula C25H19N5O2 and molecular weight 421.45.
Demonstrated preclinical activity in models of lymphoma, leukemia, and dengue virus.
For research use only; not for human or clinical use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
QL-X-138 is a small-molecule research compound that acts as a potent and selective dual inhibitor of Bruton's tyrosine kinase (BTK) and mitogen-activated protein kinase-interacting kinases (MNK). It binds covalently to BTK and non-covalently to MNK, has reported antiviral activity against dengue virus 2, and is supplied for laboratory research use only.
Potent dual inhibition of BTK and MNK.
Covalent binding to BTK and non-covalent binding to MNK.
Reported antiviral activity against dengue virus 2.
High purity (99.77%).
Available in small research quantities (1 mg, 5 mg, 10 mg; larger sizes by quote).
Recommended storage conditions provided for powder and solutions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More