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Filtered Search Results
Medchemexpress LLC eIF4A3-IN-1 | 2095486-67-0 | 100.0% | 588.88 g·mol⁻¹ | C29H23BrClN5O2 | 10 MG
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eIF4A3-IN-1 is a small-molecule inhibitor of eukaryotic initiation factor 4A-3 (eIF4A3). It binds a non-ATP site on eIF4A3, inhibits nonsense-mediated RNA decay in cellular assays, and has reported antitumor and analgesic activity. The compound is supplied as a white to off-white solid or as a DMSO solution, with high purity and recommended low-temperature storage for long-term stability.
- Selective eIF4A3 inhibitor that binds a non-ATP binding site.
- Inhibits nonsense-mediated RNA decay in cellular assays.
- Exhibits antitumor and analgesic activity in preclinical studies.
- High purity suitable for research applications.
- Available as solid or DMSO solution for convenient use.
- Recommended low-temperature storage to maintain stability.
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eMolecules 68371-97-1 | N-(4-Bromophenyl)-1,2,3,4-thiatriazol-5-amine | Apollo Scientific257.110 | C7H5BrN4S | 95.000 | Brc1ccc(Nc2nnns2)cc1 | 250mg | 562464935
N-(4-Bromophenyl)-1,2,3,4-thiatriazol-5-amine | Apollo Scientific | 68371-97-1257.110 | C7H5BrN4S | 95.000 | Brc1ccc(Nc2nnns2)cc1 | 250mg | 562464935
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eMolecules 1316273-53-6 | 2-Bromo-4-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | MFCD19105411 | 271.033 | C8H6BrF3O2 | 97.000 | OCc1ccc(OC(F)(F)F)cc1Br | 1g | 599358651
2-Bromo-4-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | 1316273-53-6 | MFCD19105411 | 271.033 | C8H6BrF3O2 | 97.000 | OCc1ccc(OC(F)(F)F)cc1Br | 1g | 599358651
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eMolecules 943332-08-9 | Medchem Express | Selumetinib (sulfate) | 50mg | 495800692 | HY-50706A | 555.76 | C17H17BrClFN4O7S
Medchem Express | Selumetinib (sulfate) | 50mg | 495800692 | HY-50706A | 943332-08-9 | 555.760 | C17H17BrClFN4O7S
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Medchemexpress LLC SSTR5 antagonist 1 | 1628741-91-2 | 99.9% | 511.59 g/mol | C28H34FN3O5 | 50 MG
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SSTR5 antagonist 1 (compound 25a) is a selective, orally available somatostatin receptor subtype 5 (SSTR5) antagonist with low-nanomolar potency and demonstrated in vitro and in vivo activity relevant to glucose regulation and insulin secretion. It shows potent activity at human SSTR5, exhibits favorable metabolic stability, high solubility, and oral efficacy in mouse models of glucose tolerance.
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Matrix Scientific 2-BROMOBENZONITRILE-25G
2-Bromobenzonitrile, 98%; 25g,C7H4BrN, MFCD00001772, mw 182.03, [2042-37-7]
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Medchemexpress LLC CE3F4 | 143703-25-7 | 98.9% | 351.01 | 1 ML
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CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with higher activity against Epac1 than Epac2(B). It effectively reduces the exchange activity of Epac1. This compound offers a targeted approach for studying Epac1-mediated pathways.
- Selective antagonist of Epac1.
- Inhibits Epac1 guanine nucleotide exchange activity.
- Does not interfere with Rap1 activity or Epac1-Rap1 interaction.
- No influence on PKA activity.
- Inhibits Epac-induced Rap1 activation in cultured HEK293 cells.
- Significantly inhibits the late phase of ERK activation stimulated by glucose in INS-1 cells.
- Inhibits atrial fibrillation and ventricular arrhythmias in animal models.
- Improves cardiac function after myocardial infarction in mice.
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Medchemexpress LLC CE3F4 selective antagonist of exchange protein directly activated by cAMP (Epac1) | 143703-25-7 | 98.9% | 351.01 | 100 MG
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CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), primarily inhibiting Epac1 with an IC50 of 10.7 μM. It also shows inhibitory activity against Epac2(B) and is intended for research use only, not for patient use.
- Selective Epac1 antagonist
- Exhibits IC50 of 10.7 μM for Epac1 and 66 μM for Epac2(B)
- More active against Epac1 than Epac2(AB) or Epac2(B) GEF activity
- Inhibits atrial fibrillation and ventricular arrhythmias in vivo
- Improves cardiac function after myocardial infarction in mice
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eMolecules 82745-18-4 | 1-(4-Bromophenyl)-3-ethylurea | MFCD00017796 | 1g
Combi-Blocks, Inc. | 1-(4-Bromophenyl)-3-ethylurea | 1g | 586079980 | YF-2986 | 98.000 | 82745-18-4 | MFCD00017796 | 243.104 | C9H11BrN2O
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eMolecules 440122-66-7 | Medchem Express | WAY-200070 | 5mg | 446256627 | HY-101271 | MFCD16618385 | 306.115 | C13H8BrNO3
Ambeed | 13-Dioxoisoindolin-2-yl cyclopentanecarboxylate | 250mg | 686659898 | A1496204 | 946513-95-7 | 259.261 | C14H13NO4
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Medchemexpress LLC 2226517-76-4 | 100MG
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2226517-76-4 | 100MG
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Medchemexpress LLC UNC-2170 100mg | 1648707-58-7 | 313.23 | C14H21BrN2O | 100 MG
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UNC-2170 is a fragment-like small-molecule ligand of 53BP1 used as a biochemical probe in DNA damage repair research. It binds selectively to 53BP1 and is applied to study recruitment to double-strand break sites.
- CAS number 1648707-58-7.
- Molecular formula C14H21BrN2O.
- Molecular weight 313.23.
- Purity 98.84% (as supplied).
- Appearance viscous liquid, colorless to light yellow.
- Target 53BP1; pathway DNA damage repair.
- Storage solid at 4°C, protect from light; in solvent store at -80°C for long term.
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eMolecules 943910-35-8 | 5-(4-Bromophenyl)-1,3-Oxazolidin-2-One | 250mg
WuXi AppTec | 5-(4-Bromophenyl)-1,3-Oxazolidin-2-One | 250mg | 583184650 | LN00245826 | 943910-35-8 | 242.072 | C9H8BrNO2
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Medchemexpress LLC GAK inhibitor 49 hydrochloride | 2930378-91-7 | 99.5% | 406.86 g/mol | C20H23ClN2O5 | 25MG
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GAK inhibitor 49 hydrochloride is the hydrochloride salt of a potent, ATP-competitive inhibitor of cyclin G-associated kinase used for biochemical and cell-based research. It exhibits subnanomolar binding affinity and cellular activity, suitable for kinase profiling and studies of GAK-related signaling.
- Potent ATP-competitive inhibitor of cyclin G-associated kinase; Ki ≈ 0.54 nM.
- Cellular activity with reported cell IC50 ≈ 56 nM.
- High reported purity (≈99.5%) suitable for research applications.
- Supplied as a solid (white to yellow) for easy handling and storage.
- Recommended storage conditions and stability guidance for solids and solutions.
- Available in small research quantities for assay development and profiling.
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Medchemexpress LLC 6-bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine | 2226517-76-4 | >98.0% | 50MG
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6-bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine | 2226517-76-4 | >98.0% | 50MG
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