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Filtered Search Results
eMolecules 1-Phenylisoquinoline | 3297-72-1 | MFCD00093934 | 25g
Combi-Blocks, Inc. | 1-Phenylisoquinoline | 25g | 589788283 | SS-2569 | 96.000 | 3297-72-1 | MFCD00093934 | 205.260 | C15H11N
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Medchemexpress LLC PI3K/mTOR Inhibitor-2 | 1848242-58-9 | 99.1% | 478.86 | 100 MG
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PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. It also exhibits antitumor activity. In MCF-7 cells, it inhibits p-AKT and p-p70s6k with IC50s of 11.6 and 89.2 nM, respectively. This compound is for research use only and has a solid appearance with a light yellow to yellow color.
- Potent dual pan-PI3K/mTOR inhibitor
- Exhibits antitumor activity
- Inhibits p-AKT and p-p70s6k in MCF-7 cells
- For research use only
- Solid appearance, light yellow to yellow color
- Molecular formula C20H13ClF2N4O4S
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![eMolecules ChemScene / 1-[3-(3-Bromophenyl)-124-oxadiazol-5-yl]methanamine / 100mg / 788447075 / CS-0123086 / 0.000 / 937651-15-5 / MFCD09034255 / 254.087 / C9H8BrN3O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502450976.PNG-250.jpg)
eMolecules ChemScene / 1-[3-(3-Bromophenyl)-124-oxadiazol-5-yl]methanamine / 100mg / 788447075 / CS-0123086 / 0.000 / 937651-15-5 / MFCD09034255 / 254.087 / C9H8BrN3O
ChemScene / 1-[3-(3-Bromophenyl)-124-oxadiazol-5-yl]methanamine / 100mg / 788447075 / CS-0123086 / 0.000 / 937651-15-5 / MFCD09034255 / 254.087 / C9H8BrN3O
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Sigma Aldrich Fine Chemicals Biosciences P7C3 >=98% (HPLC) | 301353-96-8 | MFCD00572918 | 5MG
P7C3 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 474.19 | 301353-96-8 | MFCD00572918 | 5MG
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![eMolecules Medchem Express / PI3K/mTOR Inhibitor-11 / 5mg / 788478495 / HY-151622 / / 2845104-25-6 / [null] / 443.514 / C27H21N7](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502478162.JPG-250.jpg)
eMolecules Medchem Express / PI3K/mTOR Inhibitor-11 / 5mg / 788478495 / HY-151622 / / 2845104-25-6 / [null] / 443.514 / C27H21N7
Medchem Express / PI3K/mTOR Inhibitor-11 / 5mg / 788478495 / HY-151622 / / 2845104-25-6 / [null] / 443.514 / C27H21N7
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Medchemexpress LLC HY-12759 5mg Medchemexpress, CARM1-IN-1 CAS:1020399-49-8 Purity:>98%
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Medchemexpress, HY-12759 5mg CARM1-IN-1 CAS:1020399-49-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1-(4-Bromophenyl)-2-Fluorobenzene | 40641-63-2 | MFCD04972691 | 250mg
WuXi AppTec | 1-(4-Bromophenyl)-2-Fluorobenzene | 250mg | 583190163 | LN02179900 | | 40641-63-2 | MFCD04972691 | 251.098 | C12H8BrF
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Chem-Impex International, Inc. 1,2-Dibromobenzene | MFCD00000057 | 25G
1,2-Dibromobenzene, MFCD00000057, 25G
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Ambeed 1 3Dibromobenzene
1,3-Dibromobenzene, 108-36-1, 98%
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eMolecules 3-Amino-3-(2-bromophenyl)propanoic acid | 117391-48-7 | MFCD01871297 | 1g
Apollo Scientific | 3-Amino-3-(2-bromophenyl)propanoic acid | 1g | 562437605 | OR111400 | | 117391-48-7 | MFCD01871297 | 244.088 | C9H10BrNO2
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eMolecules Ethyl 2-(3-bromophenyl)sulfanylpropanoate | 1341335-88-3 | MFCD17225270 | 1g
Oakwood Chemical | Ethyl 2-(3-bromophenyl)sulfanylpropanoate | 1g | 537704966 | 095107 | | 1341335-88-3 | MFCD17225270 | 289.190 | C11H13BrO2S
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![eMolecules Medchem Express / UNC-2170 / 5mg / 705860304 / HY-115531 / / 1648707-58-7 / [null] / 313.239 / C14H21BrN2O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502466081.JPG-250.jpg)
eMolecules Medchem Express / UNC-2170 / 5mg / 705860304 / HY-115531 / / 1648707-58-7 / [null] / 313.239 / C14H21BrN2O
Medchem Express / UNC-2170 / 5mg / 705860304 / HY-115531 / / 1648707-58-7 / [null] / 313.239 / C14H21BrN2O
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![Medchemexpress LLC Acetic acid, 2-[[4-[[(4-bromophenyl)sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]- | 518303-20-3 | MFCD03471890 | 99.7% | 468.34 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000388008-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetic acid, 2-[[4-[[(4-bromophenyl)sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]- | 518303-20-3 | MFCD03471890 | 99.7% | 468.34 | 100 MG
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UMI-77 is a selective Mcl-1 inhibitor, demonstrating high binding affinity to Mcl-1 (IC50=0.31 μM). It binds to the BH3 binding groove of Mcl-1 with a Ki of 490 nM, showcasing selectivity over other anti-apoptotic Bcl-2 family members.
- Selective Mcl-1 inhibitor.
- High binding affinity to Mcl-1 (IC50=0.31 μM).
- Binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM.
- Exhibits selectivity over other members of anti-apoptotic Bcl-2 family.
- Moderate metabolic stability with a half-life of 45 minutes.
- Demonstrates statistically significant tumor growth inhibition in vivo.
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eMolecules Ethyl 4-(4-bromophenyl)thiazole-2-carboxylate | 53101-02-3 | MFCD01924838 | 100mg
Oakwood Chemicals | Ethyl 4-(4-bromophenyl)thiazole-2-carboxylate | 100mg | 480168294 | 447186 | | 53101-02-3 | MFCD01924838 | 312.180 | C12H10BrNO2S
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![eMolecules Ethyl 2-[(4-bromophenyl)amino]acetate | 2521-92-8 | MFCD00461415 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502186872.JPG-250.jpg)
eMolecules Ethyl 2-[(4-bromophenyl)amino]acetate | 2521-92-8 | MFCD00461415 | 1g
Combi-Blocks | Ethyl 2-[(4-bromophenyl)amino]acetate | 1g | 335347744 | AN-6162 | 97.000 | 2521-92-8 | MFCD00461415 | 258.115 | C10H12BrNO2
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