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Filtered Search Results
Medchemexpress LLC SSTR5 antagonist 1 | 1628741-91-2 | 99.9% | 511.59 g/mol | C28H34FN3O5 | 50 MG
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SSTR5 antagonist 1 (compound 25a) is a selective, orally available somatostatin receptor subtype 5 (SSTR5) antagonist with low-nanomolar potency and demonstrated in vitro and in vivo activity relevant to glucose regulation and insulin secretion. It shows potent activity at human SSTR5, exhibits favorable metabolic stability, high solubility, and oral efficacy in mouse models of glucose tolerance.
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Matrix Scientific 2-BROMOBENZONITRILE-25G
2-Bromobenzonitrile, 98%; 25g,C7H4BrN, MFCD00001772, mw 182.03, [2042-37-7]
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Medchemexpress LLC CE3F4 | 143703-25-7 | 98.9% | 351.01 | 1 ML
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CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with higher activity against Epac1 than Epac2(B). It effectively reduces the exchange activity of Epac1. This compound offers a targeted approach for studying Epac1-mediated pathways.
- Selective antagonist of Epac1.
- Inhibits Epac1 guanine nucleotide exchange activity.
- Does not interfere with Rap1 activity or Epac1-Rap1 interaction.
- No influence on PKA activity.
- Inhibits Epac-induced Rap1 activation in cultured HEK293 cells.
- Significantly inhibits the late phase of ERK activation stimulated by glucose in INS-1 cells.
- Inhibits atrial fibrillation and ventricular arrhythmias in animal models.
- Improves cardiac function after myocardial infarction in mice.
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Medchemexpress LLC CE3F4 selective antagonist of exchange protein directly activated by cAMP (Epac1) | 143703-25-7 | 98.9% | 351.01 | 100 MG
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CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), primarily inhibiting Epac1 with an IC50 of 10.7 μM. It also shows inhibitory activity against Epac2(B) and is intended for research use only, not for patient use.
- Selective Epac1 antagonist
- Exhibits IC50 of 10.7 μM for Epac1 and 66 μM for Epac2(B)
- More active against Epac1 than Epac2(AB) or Epac2(B) GEF activity
- Inhibits atrial fibrillation and ventricular arrhythmias in vivo
- Improves cardiac function after myocardial infarction in mice
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Matrix Scientific 4-BROMO-2,6-DIFLUOROANILIN-25G
4-Bromo-2, 6-difluoroaniline, 98%; 25g,C6H4BrF2N, MFCD00013389, mw 208.01, [67567-26-4]
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MEDCHEMEXPRESS LLC AK-7 10MG
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501873483 AK-7 10MG
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MEDCHEMEXPRESS LLC NBD-557 5MG
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501873961 NBD-557 5MG
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Aobchem 1, 4-Dibromo-2, 5-dimethoxybenzene, AOBCHEM USA 18688-25G. 2674-34-2. MFCD00025694
1, 4-Dibromo-2, 5-dimethoxybenzene, AOBCHEM USA 18688-25G. 2674-34-2. MFCD00025694
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![eMolecules Potassium 3-(4-bromophenyl)-3-oxopropyltrifluoroborate | Combi-BlocksMFCD20327966 | 318.970 | C9H8BBrF3KO | 97.000 | [K+].F[B-](F)(F)CCC(=O)c1ccc(Br)cc1 | 1g | 267193664](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502193502.JPG-250.jpg)
eMolecules Potassium 3-(4-bromophenyl)-3-oxopropyltrifluoroborate | Combi-BlocksMFCD20327966 | 318.970 | C9H8BBrF3KO | 97.000 | [K+].F[B-](F)(F)CCC(=O)c1ccc(Br)cc1 | 1g | 267193664
Potassium 3-(4-bromophenyl)-3-oxopropyltrifluoroborate | Combi-BlocksMFCD20327966 | 318.970 | C9H8BBrF3KO | 97.000 | [K+].F[B-](F)(F)CCC(=O)c1ccc(Br)cc1 | 1g | 267193664
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eMolecules 51624-44-3 | 3-(phenylethynyl)aniline | MFCD08701708 | 1g
WuXi ChemSupply | 3-(phenylethynyl)aniline | 1g | 599171064 | LN03295005 | 95.000 | 51624-44-3 | MFCD08701708 | 193.249 | C14H11N
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Medchemexpress LLC ZD 7155 hydrochloride | 146709-78-6 | MFCD00921888; MFCD30342322 | 98.3% | 475.0 g/mol | C26H27ClN6O | 100 MG
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ZD 7155 hydrochloride is an angiotensin II type 1 (AT1) receptor antagonist provided as a research-grade analytical standard for pharmacological and cardiovascular studies. It is used in receptor binding assays, mechanistic in vitro experiments, and in vivo pharmacodynamic investigations to probe AT1-mediated pathways.
- Potent, selective AT1 receptor antagonist.
- High purity suitable for analytical and research applications.
- Available as solid and solution preparations for flexible use in assays.
- Soluble in common organic solvents such as DMSO for assay preparation.
- Suitable for in vitro receptor binding and in vivo pharmacodynamic studies.
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Matrix Scientific 4-BROMOBENZONITRILE-100G
4-Bromobenzonitrile, 97%; 100g,C7H4BrN, MFCD00001811, mw 182.03, [623-00-7]
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eMolecules 103317-32-4 | 2-(2-Bromophenyl)ethanethioamide | Combi-Blocks | MFCD09816252 | 230.120 | C8H8BrNS | 95.000 | NC(=S)Cc1ccccc1Br | 1g | 232304073
2-(2-Bromophenyl)ethanethioamide | Combi-Blocks | 103317-32-4 | MFCD09816252 | 230.120 | C8H8BrNS | 95.000 | NC(=S)Cc1ccccc1Br | 1g | 232304073
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eMolecules 831-00-5 | 2',4'-Dimethoxypropiophenone | Combi-Blocks | MFCD00027012 | 194.230 | C11H14O3 | 97.000 | CCC(=O)c1ccc(OC)cc1OC | 25g | 439373403
2',4'-Dimethoxypropiophenone | Combi-Blocks | 831-00-5 | MFCD00027012 | 194.230 | C11H14O3 | 97.000 | CCC(=O)c1ccc(OC)cc1OC | 25g | 439373403
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eMolecules 57676-50-3 | 2-(4-bromophenyl)acetohydrazide | Combi-Blocks | MFCD02612352 | 229.077 | C8H9BrN2O | 96.000 | NNC(=O)Cc1ccc(Br)cc1 | 1g | 482935189
2-(4-bromophenyl)acetohydrazide | Combi-Blocks | 57676-50-3 | MFCD02612352 | 229.077 | C8H9BrN2O | 96.000 | NNC(=O)Cc1ccc(Br)cc1 | 1g | 482935189
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