(Rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist provided for research use. It exhibits an AR binding IC50 of 26 nM and a cellular IC50 of 90 nM, and is frequently used in studies of androgenetic alopecia and AR signaling. Chemical properties include CAS 1076225-26-7, molecular formula C14H14F3NO, molecular weight 269.26 g/mol, and typical purity of 99.68%.
- Potent AR antagonist with nanomolar activity.
- Selective, nonsteroidal modulation of androgen receptor.
- High purity suitable for biochemical and cellular assays.
- Available as solid and as DMSO solution formats for convenience.
- Relevant for androgenetic alopecia and AR signaling research.