Fluorobenzenes

eMolecules​ Ethyl Bromo(4-fluorophenyl)acetate | 712-52-7 | MFCD00204082 | 1g

WuXi ChemSupply | Ethyl Bromo(4-fluorophenyl)acetate | 1g | 599165506 | LN00186371 | 95.000 | 712-52-7 | MFCD00204082 | 261.090 | C10H10BrFO2

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eMolecules​ 5-Fluoro-2-(2-fluorophenylmethoxy)phenylboronic acid | 1256358-52-7 | MFCD12634061 | 100mg

Combi-Blocks, Inc. | 5-Fluoro-2-(2-fluorophenylmethoxy)phenylboronic acid | 100mg | 603154733 | FA-4063 | 97.000 | 1256358-52-7 | MFCD12634061 | 264.030 | C13H11BF2O3

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eMolecules​ Medchem Express / LASV inhibitor 3.3 / 5mg / 783660426 / HY-124871 / / 554438-52-7 / [null] / 471.645 / C30H37N3O2

Medchem Express / LASV inhibitor 3.3 / 5mg / 783660426 / HY-124871 / / 554438-52-7 / [null] / 471.645 / C30H37N3O2

Apexbio Technology LLC Wnt agonist 1(Synonyms: Wnt Agonist I, Wnt signaling activator I, Wnt agonist compound 1, Wnt agonist-I), 10mg, CAS: 853220-52-7.

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Wnt agonist 1 (CAS 853220-52-7) is a small-molecule stimulator of the canonical Wnt signaling pathway It functions by activating -catenin-dependent transcription mediated through the TCF transcription factor with an EC50 of approximately 0 7 M In Xenopus embryos treated from developmental stage 10 5 to stage 40 with Wnt agonist 1 (10 M) notable cephalic defects including reduced head size or absent eyes were observed mirroring phenotypes associated with increased Wnt signaling Researchers use Wnt agonist 1 to investigate Wnt pathway-regulated cellular differentiation and development

Medchemexpress LLC CDK12-IN-2 | 2244987-03-7 | 99.4% | 532.64 | 100 MG

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CDK12-IN-2 is a potent, selective, and nanomolar CDK12 inhibitor (IC50=52 nM) with good physicochemical properties. It is also a strong CDK13 inhibitor, as CDK13 is the closest homologue of CDK12. It inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II and can be used as an excellent chemical probe for functional studies of CDK12.

• Potent, selective, and nanomolar CDK12 inhibitor
• Strong CDK13 inhibitor
• Excellent kinase selectivity for CDK12 over CDK2, 9, 8, and 7
• Inhibits phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II
• Useful as a chemical probe for functional studies of CDK12

Medchemexpress LLC CDK12-IN-2 | 2244987-03-7 | 99.4% | 532.64 | 50 MG

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CDK12-IN-2 is a potent, selective, and nanomolar CDK12 inhibitor with good physicochemical properties. It also acts as a strong CDK13 inhibitor and exhibits excellent kinase selectivity over CDK2, 9, 8, and 7. This compound inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II and can be used as a chemical probe for functional studies of CDK12.

• Potent, selective, and nanomolar CDK12 inhibitor (IC50=52 nM)
• Strong CDK13 inhibitor
• Excellent kinase selectivity for CDK12 over CDK2, 9, 8, and 7
• Inhibits phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II
• Can be used as a chemical probe for functional studies of CDK12
• Inhibits CTD Ser2 phosphorylation in SK-BR-3 cells (IC50 of 185 nM)
• Exhibits growth inhibition in SK-BR-3 cells (IC50 of 0.8 μM)