Fluorobenzenes
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Medchemexpress LLC F-15599 tosylate (NLX-101 tosylate) | 955112-72-8 | 567.05 | 100 MG
F-15599 tosylate is a highly selective G-protein biased 5-HT1A receptor agonist, with a Ki of 3.4 nM. It is intended for research use only.
- Highly selective G-protein biased 5-HT1A receptor agonist
- Ki of 3.4 nM
- Related to neurological, eye or ear disease research
- Can be found in compound screening libraries
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Medchemexpress LLC CDK9-IN-2 | 1263369-28-3 | 98.7% | 425.93 | 5 MG
CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8). It has an IC50 of 5 nM and 7 nM in H929 multiple myeloma (MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively. It is for research use only and not sold to patients.
- Special cyclin-dependent kinase 9 (CDK9) inhibitor.
- Extracted from patent WO/2012131594A1, compound CDKI(8).
- IC50 of 5 nM in H929 multiple myeloma (MM) cell line (72 hours).
- IC50 of 7 nM in A2058 skin cell line (72 hours).
- Reduces expression of MEPCE.
- Reduces MCL1 protein expression.
- Appearance: solid, light yellow to yellow.
- Effective in inhibiting CDK9 activity.
- Has antiproliferative activity against various cell lines including 4T1, A498, A549, AD293, BT-549, HK-2, HeLa, HepG2, Hs-578T, L02, MCF-10A, MDA-MB-231, and MRC5.