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Organic compounds that consist of benzoic acid with a methoxy group substitution; a methoxy group has an oxygen atom bonded to a methyl group. Includes compounds that are directly derived from methoxybenzoic acid.
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Methoxy-PMS (1-Methoxy PMS) is an active oxygen formation inducer and a stable electron-transport mediator. It receives an electron from NAD(P)H and passes it to tetrazolium dyes like WST-8, with no cytotoxicity in cell culture media.
Molecular weight: 336.36
Formula: C15H16N2O5S
Appearance: Solid
Color: Brown to reddish brown
Purity: 99.32%
Storage for solid: 4°C, sealed storage, away from moisture and light
Storage in solvent: -80°C for 1 year, -20°C for 6 months (sealed storage, away from moisture and light)
Solubility in DMSO: 62.5 mg/mL (185.81 mM)
Solubility in H2O: 6.67 mg/mL (19.83 mM)
Solution provided: 10 mM in 1 mL DMSO, ready for reconstitution
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Methoxy-PMS (1-Methoxy PMS) is a stable electron-transport mediator and an active oxygen formation inducer. It facilitates electron transfer between NAD(P)H and tetrazolium dyes, demonstrating no cytotoxicity in cell culture media.
Acts as an active oxygen formation inducer
Functions as a stable electron-transport mediator
Transfers electrons from NAD(P)H to tetrazolium dyes
Exhibits no cytotoxicity in cell culture media
Receives electrons from NADH or NADPH at the membrane or inside the cell
Passes electrons to WST-8 around the outer cell membrane
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1-Methoxy PMS (CAS 65162-13-2) is a redox-active small molecule utilized as an electron transfer mediator in biochemical assays Acting at the interface between NAD(P)H and tetrazolium salts 1-Methoxy PMS facilitates the controlled generation of reactive oxygen species (ROS) thereby modulating oxidative stress conditions Due to its ability to regulate cellular redox balance it is widely employed in research exploring oxidative signaling pathways ROS-mediated cellular responses and related pathophysiological processes
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