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Organic compounds that have one or more phenyl groups that are bonded to an oxygen with a radical electron; includes compounds with additional substitutions.
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KRAS inhibitor-9 is a potent inhibitor of KRAS (Kd=92 μM) that blocks the formation of GTP-KRAS and downstream activation of KRAS signaling pathways. It binds to KRAS G12D, KRAS G12C, and KRAS Q61H proteins with moderate binding affinities. This product is intended for research use only.
Causes G2/M cell cycle arrest and induces apoptosis in non-small cell lung cancer (NSCLC) cells
Selectively inhibits the proliferation of NSCLC cells with KRAS mutation but does not affect normal lung cells
Inhibits the activation of the KRAS downstream signaling pathway
Blocks GTP-KRAS formation
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Medchemexpress, HY-100523 200mg ML385 CAS:846557-71-9 Formula:C31H29N3O2S Purity:98% ML385 is a novel and specific NRF2 inhibitor. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-100523 10mg ML385 CAS:846557-71-9 ML385 is a specific nuclear factor erythroid 2-related factor 2 (NRF2) inhibitor with an IC50 of 1.9 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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CAS 1372719-93-1. 100mg. (11aR)-10111213-Tetrahydro-5-hydroxy-37-di-9-phenanthrenyl-5-oxide-diindeno[71-de17-fg][132]dioxaphosphocin min. 98%. . Molecular Weight 666.70. Molecular Formula C45H31O4P. Color/form white to light-yellow pwdr. Strem 15-1363. http//www.strem.com/catalog/v/15-1363/
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