Phenoxy compounds
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Medchemexpress LLC LYP-IN-1 | 1404436-51-6 | MFCD34567163 | 99.8% | 501.91 g/mol | C28H20ClNO6 | 5 MG
LYP-IN-1 is a potent, selective inhibitor of lymphoid tyrosine phosphatase used in biochemical and cellular studies to probe T-cell and mast cell signaling. The compound contains an alkyne moiety enabling copper-catalyzed azide-alkyne cycloaddition for probe development and labeling in chemical biology applications.
- Potent and selective LYP inhibition (Ki 110 nM; IC50 0.259 μM).
- Alkyne handle for copper-catalyzed click chemistry applications.
- High purity suitable for biochemical and cellular assays.
- Soluble in DMSO up to 2 mg/mL with mild heating and sonication.
- Stable when stored as powder at -20°C for extended periods.
2
Medchemexpress LLC Epertinib hydrochloride | 2071195-74-7 | 98.2% | 596.48 g/mol | C30H28Cl2FN5O3 | 100 MG
Epertinib hydrochloride is the hydrochloride salt of epertinib, a potent, orally active, reversible, and selective inhibitor of EGFR, HER2, and HER4. It is provided for preclinical research to evaluate signaling pathways and antitumor efficacy and is compatible with click-chemistry applications because of an alkyne functional group.
- Potent, selective tyrosine kinase inhibitor of EGFR, HER2, and HER4.
- Used in preclinical antitumor and signaling research.
- Contains an alkyne moiety compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Supplied as a light yellow to yellow solid with high purity.
- Stable under recommended storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Molecular weight 596.48 g/mol; molecular formula C30H28Cl2FN5O3.