Phenylcarbamic acid esters
Medchemexpress LLC SULT1E1 protein, human, recombinant, N-terminal His tag | >95.0% | 5 UG
Recombinant human SULT1E1 (estrogen sulfotransferase) expressed in E. coli with an N-terminal His tag. Supplied lyophilized for biochemical and enzymatic assays, the protein sulfates estradiol, estrone, DHEA, pregnenolone, and xenobiotics; the product includes activity data and low endotoxin suitable for in vitro studies.
- Human-derived recombinant protein with N-terminal His tag.
- Supplied amount: 5 μg lyophilized.
- Purity greater than 95% by reducing SDS-PAGE.
- Molecular weight approx. 36 kDa; sequence N2-I294.
- Specific activity 74.44 pmol/min/μg (PAPS → 1-napthol, 37 °C, 20 min).
- Endotoxin <1 EU/μg (LAL).
- Formulated in Tris-HCl, NaCl, and 8% trehalose; 0.22 μm filtered before lyophilization.
- Store at -20 °C; after reconstitution stable at 4 °C for 1 week.
Medchemexpress LLC 4-(4-Aminophenyl)morpholin-3-one | 438056-69-0 | 100.0% | C10H12N2O2 | 50 G
4-(4-Aminophenyl)morpholin-3-one is a drug intermediate for the synthesis of various active compounds. This product is a high-purity chemical useful in various research and development settings.
- Molecular weight: 192.22
- Molecular formula: C10H12N2O2
- CAS number: 438056-69-0
- Appearance: Solid, white to light brown
- Purity: 100.0%
- Ships at room temperature in the continental US
- Storage for powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC N-Boc-N-bis(PEG4-acid) | 2093152-88-4 | 97.0% | C27H51NO14 | 25 MG
N-Boc-N-bis(PEG4-acid) is a PROTAC linker, specifically a PEG-based type, designed for use in the synthesis of PROTACs. PROTACs are compounds that utilize the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins. This is achieved by connecting two different ligands via a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets the protein intended for degradation.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- PROTACs employ the ubiquitin-proteasome system to degrade target proteins.
- PROTACs consist of two ligands connected by a linker, targeting an E3 ubiquitin ligase and a protein of interest.
Medchemexpress LLC Nh-bis(peg2-c2-boc) | 1964503-36-3 | >=98.0% | C22H43NO8 | 25 MG
Nh-bis(peg2-c2-boc) is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds designed to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins, functioning by connecting an E3 ubiquitin ligase ligand to a target protein ligand via a linker.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Boc-NH-PEG7-acid | 2055044-68-1 | C22H43NO11 | 250 MG
Boc-NH-PEG7-acid is a PEG-based PROTAC linker primarily utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC 4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester | 1309460-29-4 | ≥98.0% | C18H34O9 | 250 MG
Acid-PEG5-C2-Boc is a product that appears as a colorless to light yellow liquid. It has been tested and complies with the given specifications. It is recommended for research use only and has not been fully validated for medical applications. Molecular Weight: 394.46.
- Appearance: Colorless to light yellow liquid
- Purity (NMR): ≥98.0%
- Storage: -20°C for 3 years; 4°C for 2 years (pure form)
- Storage: -80°C for 6 months; -20°C for 1 month (in solvent)
Medchemexpress LLC Amino-PEG24-Boc | 2170987-96-7 | 99.81% | C55H111NO26 | 25 MG
Amino-PEG24-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase and the other to the target protein.
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
- PEG-based linker
- Intended for research use only
Medchemexpress LLC 5,8,11,14-tetraoxa-2-azahexadecanoic acid, 16-amino-, 1,1-dimethylethyl ester | 811442-84-9 | ≥98.0% | 336.42 g/mol | C15H32N2O6 | 25 G
Boc-protected PEG4 diamine used as a cleavable PEG spacer and linker in antibody-drug conjugate and PROTAC synthesis. It provides a terminal primary amine for conjugation and a Boc-protected site for selective deprotection.
- Boc-protected terminal amine for selective deprotection.
- PEG4 spacer for improved solubility and flexibility.
- Suitable for ADC and PROTAC linker synthesis.
- High purity (≥98.0% by NMR).
- Monodisperse PEG chain with predictable molecular weight.
Medchemexpress LLC Boc-C14-COOH | 843666-27-3 | ≥98.0% | 342.51 g/mol | C20H38O4 | 5 G
Boc-C14-COOH is a Boc-protected C14 carboxylic acid used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as an alkyl chain linker in PROTAC construction. It is supplied as a powder with characterized solubility and storage recommendations.
- Used as a non-cleavable ADC linker and PROTAC linker.
- Powder form with specified storage conditions for powder and solutions.
- Soluble in DMSO (200 mg/mL) for in vitro use; formulations for in vivo use are documented.
- Molecular weight 342.51 g/mol and formula C20H38O4 for formulation calculations.
- Available in small laboratory quantities and larger pack sizes per vendor listing.