Phenylcarbamic acid esters
Medchemexpress LLC Bromo-PEG8-Boc | 1623792-00-6 | 99.86% | C23H45BrO10 | 500 MG
Bromo-PEG8-Boc is a PEG-based PROTAC linker essential for the synthesis of Proteolysis-Targeting Chimeras (PROTACs). PROTACs are designed to contain two distinct ligands, one for an E3 ubiquitin ligase and another for a target protein, connected by a linker. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system, enabling the selective degradation of specific target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Applicable in cancer research
- Supports targeted therapy
Medchemexpress LLC N-Boc-4-hydroxy-L-proline methyl ester | 102195-79-9 | >=98.0% | 245.28 g·mol⁻1 | C11H19NO5 | 25 G
N-Boc-4-hydroxy-L-proline methyl ester is a Boc-protected hydroxyproline derivative supplied as a research-grade building block used in medicinal chemistry and linker synthesis for ADCs and PROTACs.
- Used as a non-cleavable ADC linker building block
- Suitable for PROTAC linker synthesis
- Boc-protected hydroxyproline methyl ester functional group enables selective transformations
- Provided in gram-scale quantities for synthesis and scale-up
Medchemexpress LLC (S)-3-(Boc-amino)-4-phenylbutyric acid | 51871-62-6 | MFCD01076271 | ≥95.0% | 279.33 g/mol | C15H21NO4 | 1 G
(S)-3-(Boc-amino)-4-phenylbutyric acid is a Boc-protected phenylalanine derivative used as a research reagent and synthetic intermediate. It is supplied as a white to off-white solid and is commonly used in peptide synthesis and medicinal chemistry.
- Appearance: White to off-white solid.
- CAS number: 51871-62-6.
- Molecular formula: C15H21NO4.
- Molecular weight: 279.33 g/mol.
- Purity: ≥95.0%.
- Available pack sizes: 250 mg, 1 g, 5 g, 10 g, 25 g.
- Storage: Powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Boc-C16-cooh | 843666-40-0 | 100.0% | 370.57 g/mol | C22H42O4 | 500 MG
Boc-C16-COOH is a Boc-protected long-chain carboxylic acid used as a non-cleavable antibody-drug conjugate (ADC) linker and as an alkyl-chain PROTAC linker for chemical synthesis. It is supplied as a white to off-white solid with high purity and is soluble in DMSO for stock solutions.
- Non-cleavable ADC and PROTAC linker
- High purity (99.98%)
- Molecular weight 370.57 g/mol
- Cas number 843666-40-0
- Soluble in DMSO: 100 mg/mL; ultrasonic and gentle heating (to 60°C) may improve solubility
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)
- Appearance: white to off-white solid
- Available unit: 500 MG
Medchemexpress LLC Boc-C14-COOH | 843666-27-3 | MFCD23136039 | ≥98.0% | 342.51 g/mol | C20H38O4 | 25 G
Boc-protected C14 alkyl-chain carboxylic acid used as a non-cleavable linker in antibody-drug conjugate synthesis and as an alkyl-chain PROTAC linker. Supplied as a solid for research use.
- Non-cleavable linker for ADC synthesis.
- Suitable as an alkyl-chain PROTAC linker.
- Purity ≥98.0% and molecular weight 342.51 g/mol.
- Molecular formula C20H38O4.
- Available as a 25 G solid for research applications.
Medchemexpress LLC Acid-PEG3-C2-Boc | 1807539-06-5 | ≥97.0% | 100 MG
Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker. It can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg- and alkyl/ether-based protac linker
- Can be used in the synthesis of protacs
- Potential for degradation of egfr
- Potential for inhibition of mtor
Medchemexpress LLC Neuritin Human N-H 50ug
Recombinant human Neuritin (partial length) with an N-terminal His tag, expressed in E. coli. This ~11 kDa protein promotes neurite outgrowth and synaptic plasticity and is supplied as a lyophilized powder formulated in Tris-NaCl buffer. It is intended for in vitro assays, biochemical characterization, and protein interaction studies; store frozen and follow recommended reconstitution and stabilizer guidelines for best results.
- Expressed in E. coli and supplied with an N-terminal His tag.
- Approximately 11 kDa partial-length protein that promotes neurite growth.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Lyophilized formulation in 50 mM Tris-HCl, 300 mM NaCl, pH 7.4.
- Stable when stored at -20°C; aliquot and freeze for long-term storage.
- Recommended reconstitution at ≥100 μg/mL with carrier protein for stability.
Medchemexpress LLC Tert-butyl 1-bromo-3,6,9,12-tetraoxapentadecan-15-oate | 564476-32-0 | MFCD22574808 | 98.0% | 385.29 g/mol | C15H29BrO6 | 5 G
Br-PEG4-C2-Boc is a cleavable 4-unit polyethylene glycol (PEG) linker containing a bromoacetamido reactive handle and a Boc-protected terminal group, used in the synthesis of antibody-drug conjugates, PROTACs, and other bioconjugates in research settings.
- Cleavable PEG4 linker suitable for conjugation chemistry.
- Bromo group provides a reactive handle for alkylation and coupling.
- Boc-protected terminal group enables controlled deprotection after conjugation.
- High purity suitable for synthetic research applications.
- Provided as a solid in multiple pack sizes for flexible workflows.
Medchemexpress LLC CCL6 Rat N-His 2ug
The CCL6 protein is part of the intercrine beta family a component of chemokines involved in intercellular communication and immune responses In this family CCL6 may play an important role in regulating inflammatory processes and cellular interactions CCL6 Protein Rat (N-His) is the recombinant rat-derived CCL6 protein expressed by E coli with N-6 His labeled tag
Medchemexpress LLC (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)-1-methylpiperidine | 110429-36-2 | MFCD03788781 | 10g
N-Methylparoxetine is a derivative of Paroxetine that induces Apoptosis NSCLC cells by activating mitogen-activated protein kinase ( MAPK) N-Methylparoxetine has antitumor activity[1]
Medchemexpress LLC MicroRNA Antagomir N 20nmol | 20nmol
MicroRNA Antagomir Negative Control is a chemically-modified oligonucleotide (2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 1 cholesterol group at the 3 end and full-length nucleotide 2 -methoxy modification) and can be used as a negative control The sequence of MicroRNA Antagomir Negative Control is derived from cel-mir-239b It has minimal sequence identity with miRNAs in human mouse and rat
Medchemexpress LLC 13,13-dimethyl-11-oxo-4,7,12-trioxa-10-azatetradecanoic acid | 1365655-91-9 | MFCD22056304 | 98.0% | 277.31 g/mol | C12H23NO6 | 25 G
Boc-NH-PEG2-CH2CH2COOH is a Boc-protected PEG2 linker with a terminal carboxylic acid used for constructing PROTACs and other small-molecule conjugates. It offers a short, hydrophilic spacer and a protected amine for selective coupling and downstream deprotection.
- Boc-protected amino group for orthogonal protection.
- Terminal carboxylic acid for standard amide coupling.
- Short PEG2 spacer increases solubility and conformational flexibility.
- High purity suitable for research synthesis and derivatization.
- Liquid form and defined density facilitate solution preparation.
Medchemexpress LLC Benzenamine-13C6, 4-iodo | 233600-80-1 | 99.2% | 224.98 | 13C6H6IN | 10 MG
4-Iodoaniline-13C6 is the 13C6-labeled analogue of 4-iodoaniline provided as a stable isotope reference and research reagent. It serves as an internal standard and synthetic intermediate for analytical and preparative applications, particularly in studies related to methemoglobinemia, glycogen phosphorylase inhibitor synthesis, and liver or blood disease research. The labeled compound has formula 13C6H6IN, CAS 233600-80-1, and molecular weight 224.98 g/mol.
- Stable 13C6 isotopic labeling for accurate mass spectrometry quantification.
- High chemical purity suitable for analytical and synthetic use.
- Supplied in milligram quantities appropriate for tracer and reference applications.
- Compatible with LC-MS and GC-MS workflows as an internal standard.
- Useful as a building block for organic synthesis and method development.
eMolecules Key Organics/BIONET Phenylboronic acid 1mg 564101482 AS-2259 95 000 98-80-6 MFCD00002103 121 930 C6H7BO2
Key Organics/BIONET Phenylboronic acid 1mg 564101482 AS-2259 95 000 98-80-6 MFCD00002103 121 930 C6H7BO2