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Organic compounds that consist of a phenylcarbamic acid where the hydrogen atom bonded to the oxygen atom is replaced with an organic group; phenylcarbamic acid a carboxylic acid bonded to an amino group with a phenyl group substitution.
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N-Boc-N-bis(PEG4-acid) is a PROTAC linker, specifically a PEG-based type, designed for use in the synthesis of PROTACs. PROTACs are compounds that utilize the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins. This is achieved by connecting two different ligands via a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets the protein intended for degradation.
Peg-based PROTAC linker.
Used in the synthesis of PROTACs.
PROTACs employ the ubiquitin-proteasome system to degrade target proteins.
PROTACs consist of two ligands connected by a linker, targeting an E3 ubiquitin ligase and a protein of interest.
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Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Alkyl chain-based PROTAC linker
Used in the synthesis of PROTACs
PROTACs utilize the ubiquitin-proteasome system
Target protein degradation
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N,N,N-Trimethylhexadecan-1-aminium-d42 (chloride) is a solid chemical product intended for use as a laboratory chemical and in the manufacture of various substances. It is identified by CAS number 2095863-88-8 and has a molecular weight of 362.26.
Store at 4°C, sealed, away from moisture.
For storage in solvent: -80°C for 6 months, or -20°C for 1 month (sealed storage, away from moisture).
Shipping at room temperature is suitable if less than 2 weeks.
Not identified as a hazardous substance or mixture.
Purity (HPLC) is 99.60%.
Isotopic enrichment is 98.97%.
Product has been tested and complies with specifications.
For research use only; not fully validated for medical applications.
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