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Organic compounds that consist of a phenylcarbamic acid where the hydrogen atom bonded to the oxygen atom is replaced with an organic group; phenylcarbamic acid a carboxylic acid bonded to an amino group with a phenyl group substitution.
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NH-bis(C1-PEG1-Boc) from MedChemExpress is a chemical compound with the molecular formula C17H33NO6 and a molecular weight of 347.45. It is stored at 4°C, sealed, and protected from moisture and light. In solvent, it can be stored at -80°C for 6 months or -20°C for 1 month under similar conditions.
Appearance: Colorless to light yellow liquid
1H NMR spectrum consistent with structure
LCMS consistent with structure
Purity of 99.72% by HPLC
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NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. This compound is a key component in creating PROTACs, which are molecules designed to selectively degrade target proteins within a cell.
Alkyl/ether-based PROTAC linker
Used in the synthesis of PROTACs
PROTACs contain two different ligands connected by a linker
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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