Phenylcarbamic acid esters
Medchemexpress LLC Boc-NH-C4-Br | 164365-88-2 | 252.15 | 25 G
Boc-NH-C4-Br is an alkyl chain-based PROTAC linker primarily used in the synthesis of PROTACs (Proteolysis Targeting Chimeras). PROTACs are designed with two distinct ligands connected by a linker. One ligand is specific for an E3 ubiquitin ligase, and the other targets a protein of interest.
- Leverages the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC Br-PEG4-CH2-Boc | 1807505-29-8 | ≥97.0% | 5 G
Br-PEG4-CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. These PROTACs feature two distinct ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- PEG- and Alkyl/ether-based linker
- Facilitates PROTAC synthesis
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Molecular weight of 371.26
- Chemical formula: C14H27BrO6
- Appears as a colorless to light yellow liquid
- Purity of ≥97.0%
- Relevant for cancer and cancer targeted therapy research
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