Phenylhydrazines
Search Within Results
391
–
405
of
1,697
results
391
392
393
Medchemexpress LLC Almonertinib (hydrochloride) | 2134096-03-8 | 98.9% | 562.11 | 50 MG
Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor. It exhibits high selectivity for EGFR-sensitizing and T790M resistance mutations and is utilized in non-small cell lung cancer research. It can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R, and L861Q.
- Orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor
- High selectivity for EGFR-sensitizing and T790M resistance mutations
- Potent inhibitory activity against T790M (IC50: 0.37 nM), T790M/L858R (IC50: 0.29 nM), and T790M/Del19 (IC50: 0.21 nM)
- Less effective against wild-type EGFR (IC50: 3.39 nM)
- Used for research in non-small cell lung cancer (NSCLC)
- Inhibits other EGFR sensitive mutations such as G719X, del19, L858R, and L861Q
394
395
396
397
398
399
400
401
402
Medchemexpress LLC Omadacycline hydrochloride | 1196800-39-1 | 99.47% | 593.11 | 1 ML
Omadacycline hydrochloride | 1196800-39-1 | 99.47% | 593.11 | 1 ML
403
404
405