Phenylhydrazines
Medchemexpress LLC Promethazine hydrochloride | 58-33-3 | MFCD00012652 | 99% | 320.88 | 500 MG
Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. It is a potent H1 receptor antagonist and a mAChR antagonist, also showing affinity for 5-HT2A and 5-HT2C receptors.
- Inhibits adipocyte formation in a dose-dependent manner
- Decreases expression of peroxisome proliferator activated receptor γ (PPARG)
- Reduces phosphorylation level of CREB in PDGFRα+ cells
- Possesses inhibitory effect on ectopic fat cell formation in skeletal muscle in a mouse achilles tendon rupture model
- Potent H1 receptor antagonist
- mAChR antagonist
- Shows affinity for 5-HT2A and 5-HT2C receptors
Medchemexpress LLC Valacyclovir (hydrochloride) | 124832-27-5 | 99.9% | 360.80 | 25 MG
Valacyclovir hydrochloride is an orally active antiviral agent effective against herpes simplex, herpes zoster, and herpes B. It acts as a proagent of Aciclovir, inhibiting HSV-1. Its uptake is concentration dependent and saturable, suggesting hPEPT1 dominates its intestinal transport in vitro. Clinical trials show its effectiveness in treating genital herpes and recurrences, with a 1 g daily dose being as effective as 2 g daily.
- Orally active antiviral agent
- Effective against herpes simplex, herpes zoster, and herpes B
- Inhibits HSV-1 with an IC50 of 2.9 μg/ml
- Proagent of Aciclovir
- Uptake is concentration dependent and saturable
- Effective for treating genital herpes and recurrences
- Daily dose of 1 g is as effective as 2 g daily
Medchemexpress LLC (2S,4R)-4-methylglutamic acid | 31137-74-3 | MFCD00937765 | ≥97.0% | 161.16 g/mol | C6H11NO4 | 100 MG
SYM 2081 ((2S,4R)-4-methylglutamic acid, CAS 31137-74-3) is a selective kainate receptor agonist used as a research tool in neuroscience and pharmacology. It modulates glutamate transport and receptor activity, and has been employed in studies of neuroprotection and inflammatory or neuropathic pain. Supplied as a solid for laboratory use, it is typically stored at -20°C.
- Selective kainate receptor agonist for receptor pharmacology studies.
- Modulates glutamate transport and excitatory amino acid uptake.
- Applied in models of neuroprotection and pain research.
- Suitable for in vitro and in vivo experimental use in small research quantities.
- Solid form with recommended storage at -20°C to preserve stability.
