Phenylhydrazines
Medchemexpress LLC Hydroxylamine, O-methyl-, hydrochloride (1:1) | 593-56-6 | MFCD00012951 | 98.0% | 83.52 | CH6ClNO | 50g
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor Methoxyamine hydrochloride binds to 3 hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents[1][2]
Medchemexpress LLC Methacycline hydrochloride | 3963-95-9 | MFCD04972012 | 99.7% | 500 MG
Methacycline hydrochloride is a tetracycline antibiotic known for its ability to inhibit bacterial protein synthesis. It also acts as a potent epithelial-mesenchymal transition (EMT) inhibitor, effectively blocking EMT in vitro and fibrogenesis in vivo without directly impacting TGF-β1 Smad signaling. This antimicrobial agent also shows potential in the context of pulmonary fibrosis.
- Inhibits bacterial protein synthesis
- Acts as a potent epithelial-mesenchymal transition (EMT) inhibitor
- Blocks EMT in vitro
- Blocks fibrogenesis in vivo
- Antimicrobial properties
- Potential for pulmonary fibrosis studies
Medchemexpress LLC Hydrastinine hydrochloride | 4884-68-8 | MFCD09763656 | 99.41% | 1 ML
Hydrastinine hydrochloride is a major alkaloid component found in goldenseal (Hydrastis canadensis) and functions as a haemostatic agent.
- Major alkaloid constituent in goldenseal (Hydrastis canadensis).
- Can be used as a haemostatic agent.
Medchemexpress LLC Padoprazanum hydrochloride | 2940882-02-8 | 98.7% | 441.90 | 50 MG
Padoprazanum hydrochloride is a proton pump inhibitor primarily intended for research purposes.
- For research use only.
- Not for patient use.
- Appears as an off-white to light yellow solid.
- Requires storage at room temperature, dry and cool conditions.
- In solvent, store at -80°C for one year or -20°C for six months.
Medchemexpress LLC Thioridazine hydrochloride | 130-61-0 | 100.0% | 10 MM * 1 ML
Thioridazine hydrochloride is an orally active antagonist of dopamine receptor D2 family proteins, exhibiting potent anti-psychotic and anti-anxiety activities. It also acts as a potent inhibitor of PI3K-Akt-mTOR signaling pathways, demonstrating anti-angiogenic effects. This compound shows antiproliferative and apoptosis induction effects in various types of cancer cells, specifically targeting cancer stem cells (CSCs).
- Orally active dopamine receptor D2 antagonist
- Potent anti-psychotic and anti-anxiety agent
- Inhibits PI3K-Akt-mTOR signaling pathways
- Exhibits anti-angiogenic effects
- Induces antiproliferative and apoptosis in cancer cells
- Targets cancer stem cells
- Soluble in water (100 mg/mL) and DMSO (≥ 45 mg/mL)
- Stable at 4°C in sealed storage
- In solvent, stable for 6 months at -80°C or 1 month at -20°C