Phenylhydrazines
Accela Chembio Inc 3-fluorophenylhydrazine Hydrochloride | 25g | 2924-16-5 | MFCD00012934 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
3-fluorophenylhydrazine Hydrochloride | 25g | 2924-16-5 | MFCD00012934 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
Medchemexpress LLC Pyridostatin hydrochloride | 1781882-65-2 | C31H37Cl5N8O5 | 5 MG
Pyridostatin hydrochloride is a G-quadruplex DNA stabilizing agent that targets DNA and RNA G4s in cells. It promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. This selective G-quadruplex DNA-binding small molecule also targets the proto-oncogene Src, reducing SRC protein levels and cellular motility in human breast cancer cells.
- G-quadruplex DNA stabilizing agent (Kd=490 nM)
- Targets DNA and RNA G4s in cells
- Promotes growth arrest in human cancer cells
- Induces replication- and transcription-dependent DNA damage
- Targets proto-oncogene Src
- Reduces SRC protein levels and cellular motility
- Causes neurite retraction, synaptic loss, and neuronal death
- Induces formation of DNA DSBs
- Downregulates BRCA1 protein at transcriptional level
Medchemexpress LLC Pyridostatin hydrochloride | 1781882-65-2 | C31H37Cl5N8O5 | 100 MG
Pyridostatin hydrochloride is a potent G-quadruplex DNA stabilizing agent that targets DNA and RNA G4s within cells. It effectively promotes growth arrest in various human cancer cells by inducing replication- and transcription-dependent DNA damage. This highly selective molecule also specifically targets the proto-oncogene Src, leading to a reduction in SRC protein levels and SRC-dependent cellular motility, particularly in human breast cancer cells.
- Stabilizes G-quadruplex DNA (Kd=490 nM)
- Targets DNA and RNA G4s in cellular environments
- Promotes growth arrest in human cancer cells
- Induces replication- and transcription-dependent DNA damage
- Reduces SRC protein levels and cellular motility in breast cancer cells
- Highly selective G-quadruplex DNA-binding small molecule
- Induces cell cycle arrest in over 60 cancer cell lines
- Downregulates the BRCA1 protein transcriptionally
Medchemexpress LLC Besifloxacin (Hydrochloride) | 405165-61-9 | 98.5% | 430.30 | 25 MG
Besifloxacin Hydrochloride is a fourth-generation fluoroquinolone antibiotic that functions as a DNA gyrase and topoisomerase IV inhibitor. It exhibits broad-spectrum antibacterial activity against Gram-negative and Gram-positive aerobic and anaerobic strains and helps reduce the incidence of drug resistance. It also possesses anti-inflammatory properties and can be utilized in bacterial conjunctivitis research.
- Functions as a DNA gyrase and topoisomerase IV inhibitor.
- Exhibits broad-spectrum antibacterial activity against Gram-negative and Gram-positive aerobic and anaerobic strains.
- Reduces the incidence of drug resistance.
- Possesses anti-inflammatory activity.
- Can be used in bacterial conjunctivitis research.
Sigma Aldrich Fine Chemicals Biosciences 4-Chlorophenylhydrazine hydrochloride 98% | 1073-70-7 | MFCD00012943 | 5G
4-Chlorophenylhydrazine hydrochloride 98% | Purity: 98% | Mol Wt: 179.05 | 1073-70-7 | MFCD00012943 | 5G
Aobchem 4-Bromophenylhydrazine hydrochloride, AOBCHEM USA 25784-100G. 622-88-8. MFCD00012941
4-Bromophenylhydrazine hydrochloride, AOBCHEM USA 25784-100G. 622-88-8. MFCD00012941