Styrenes
![Medchemexpress LLC Benzonitrile, 4-[5-chloro-7-[[(1R)-1,2,2-trimethylpropyl]amino]triazolo[1,5-a]pyrimidin-6-yl]-3,5-difluoro- | 2699937-76-1 | 99.5% | 390.82 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387325-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzonitrile, 4-[5-chloro-7-[[(1R)-1,2,2-trimethylpropyl]amino]triazolo[1,5-a]pyrimidin-6-yl]-3,5-difluoro- | 2699937-76-1 | 99.5% | 390.82 | 5 MG
Microtubule stabilizer-1 (compound 69) is a brain-penetrant microtubule (MT) stabilizer. It increases acetylated α-tubulin (AcTub) levels and prevents the characteristic loss of neuronal MTs observed after incubation with Okadaic acid. This compound can be used for the study of Alzheimer's disease (AD) and related neurodegenerative tauopathies.
- Brain-penetrant microtubule (MT) stabilizer
- Increases acetylated α-tubulin (AcTub) levels
- Prevents loss of neuronal MTs after Okadaic acid incubation
- Used for Alzheimer's disease (AD) and neurodegenerative tauopathies research
TARGETMOL CHEMICALS INC BETA-EUDESMOL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. beta-Eudesmol (Beta-Selinenol) is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a variety of plants including Cannabis and has diverse biological activities. purity: 99%
Medchemexpress LLC K858 racemic | 72926-24-0 | MFCD00181155 | 99.8% | 277.35 g·mol⁻1 | C13H15N3O2S | 10 MG
K858 (racemic) is a small-molecule ATP-uncompetitive inhibitor of the mitotic kinesin Eg5 with an IC50 of 1.3 μM. Supplied as a solid powder, it is intended for cellular and biochemical research into mitosis, spindle dynamics, and antiproliferative mechanisms. Manufacturer guidance includes solubility and in vivo formulation protocols for experimental use.
- ATP-uncompetitive inhibitor of kinesin Eg5 (IC50 1.3 μM).
- High purity (99.8%).
- Solid powder form suitable for laboratory handling.
- Soluble in DMSO up to 100 mg/mL; ultrasonic assistance recommended.
- Includes in vivo formulation protocols for dosing studies.
- Available in small research quantities for preclinical experiments.
TARGETMOL CHEMICALS INC BETA-AMYLOID 25-35 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. (beta)-Amyloid (25-35) (A(beta)25-35) is the fragment A(beta)(25-35) of the Alzheimer's amyloid (beta)-peptide. Which has shown neurotoxic activities in cultured cells. purity: 97%
Sigma Aldrich Fine Chemicals Biosciences 1,6-Diphenyl-1,3,5-hexatriene 98% | 1720-32-7 | MFCD00004793 | 5G
1,6-Diphenyl-1,3,5-hexatriene 98% | Purity: 98% | Mol Wt: 232.32 | 1720-32-7 | MFCD00004793 | 5G
Medchemexpress LLC CFTR(inh)-172 | 307510-92-5 | 99.8% | 409.40 | 1 MG
CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel. It reversibly inhibits CFTR short-circuit current in less than 2 minutes with a Ki of 300 nM. The inhibition is complete in approximately 10 minutes (t1/2=4 minutes) and is reversed after washout with a t1/2 of approximately 5 minutes. It is nontoxic to FRT cells after 24 hours at concentrations up to 100 μM. It reduces open probability by > 90% and significantly reduces cholera toxin-induced fluid secretion in mouse models.
- Potent and selective blocker of the CFTR chloride channel.
- Reversibly inhibits CFTR short-circuit current.
- Nontoxic to FRT cells at concentrations up to 100 μM.
- Reduces open probability of CFTR by > 90%.
- Reduces cholera toxin-induced fluid secretion in mouse models.
Medchemexpress LLC Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) | 90.0% | 50 MG
Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) is a diblock copolymer utilized in the preparation of polymer micelles or vesicles and other encapsulation applications. This product is intended for research use only.
- Solid appearance
- White to off-white color
- Soluble in DMF (25 mg/mL with ultrasonic) and THF (20 mg/mL with ultrasonic)
- Ships at room temperature in continental US
- Storage as powder at -20°C for 3 years
- Storage in solvent at -80°C for 6 months, -20°C for 1 month
TARGETMOL CHEMICALS INC TAK-653 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. TAK-653 a selective positive allosteric modulator (PAM) of AMPA receptors exhibiting minimal agonistic activity elicits an antidepressant-like response while maintaining a favorable safety profile in rat models. purity: 99%
![Medchemexpress LLC (4R)-1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-be | 1884712-47-3 | MFCD30489741 | 99.9% | 386.45 | C22H22N6O | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213781.png-250.jpg)
Medchemexpress LLC (4R)-1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-be | 1884712-47-3 | MFCD30489741 | 99.9% | 386.45 | C22H22N6O | 50 MG
CPI-637 is a selective, cell-active benzodiazepinone inhibitor of the CBP and EP300 bromodomains used as a research reagent for epigenetic and cancer-biology studies. It shows nanomolar biochemical potency and cellular target engagement and is supplied as a high-purity solid for laboratory use.
- Selective CBP/EP300 bromodomain inhibition (CBP IC50 ≈ 0.03 μM; EP300 IC50 ≈ 0.051 μM).
- Low activity against BRD4 BD-1 (IC50 ≈ 11.0 μM), indicating >700-fold selectivity.
- Cellular activity with CBP BRET EC50 ≈ 0.3 μM.
- High purity solid suitable for biochemical and cellular assays.
- Stable under recommended storage conditions (powder: -20°C; in solvent: -80°C).
- Available in small research package sizes (for example, 50 mg).
![eMolecules 21370-71-8 | trans-1-Decalone | Oakwood Chemical304.474 | C20H32O2O=C1CCC[C@H]2CCCC[C@H]12.O=C1CCC[C@@H]2CCCC[C@@H]12 | 100mg | 537719759](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502143062.JPG-250.jpg)
eMolecules 21370-71-8 | trans-1-Decalone | Oakwood Chemical304.474 | C20H32O2O=C1CCC[C@H]2CCCC[C@H]12.O=C1CCC[C@@H]2CCCC[C@@H]12 | 100mg | 537719759
trans-1-Decalone | Oakwood Chemical | 21370-71-8304.474 | C20H32O2O=C1CCC[C@H]2CCCC[C@H]12.O=C1CCC[C@@H]2CCCC[C@@H]12 | 100mg | 537719759