Aminophenols
Medchemexpress LLC YIL781 hydrochloride | 1640226-17-0 | 99.48% | 445.96 | 25 MG
YIL781 hydrochloride is a potent, orally active ghrelin receptor (GHSR) antagonist. It has been shown to improve glucose homeostasis in rats and effectively inhibits the calcium response induced by ghrelin.
- Potent and orally active ghrelin receptor (GHSR) antagonist.
- Produces a greater improvement in glucose homeostasis in rats.
- Inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27.
- For research use only.
Medchemexpress LLC Fasudil hydrochloride | 105628-07-7 | MFCD00943198 | 100.0% | 327.83 g/mol | C14H18ClN3O2S | 1 G
Fasudil hydrochloride is the hydrochloride salt of fasudil, a small-molecule Rho kinase (ROCK) inhibitor used in biochemical and cellular research to probe cytoskeletal dynamics, vascular tone, and related signaling pathways. It is provided as a high-purity solid suitable for laboratory research.
- RhoA/ROCK inhibitor for biochemical and cellular studies.
- CAS number 105628-07-7 and molecular weight 327.83 g/mol.
- Molecular formula C14H18ClN3O2S.
- High purity (~99.97%) suitable for research use.
- Solid, white to off-white appearance; soluble in DMSO and water.
- Recommended storage: 4°C sealed; in solvent: -80°C (1 year) or -20°C (6 months).
- Offered in laboratory pack sizes including 1 g.
Medchemexpress LLC AZD9056 hydrochloride | 345303-91-5 | 98.2% | 455.46 | 5 MG
AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases. It is for research use only.
- Selective orally active inhibitor of P2X7
- Plays a significant role in inflammation and pain-causing diseases
- Has a clear inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells
- Exerts pain-relieving and anti-inflammatory effects
- Reverses the upregulated expression of interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), matrix metalloproteinase-13 (MMP-13), substance P (SP) and prostaglandin E2 (PGE2) which is induced by MIA in cartilage tissues
Medchemexpress LLC 4-((4-(4-chlorophenyl)-2-thiazolyl)amino)phenol | 312636-16-1 | MFCD00733553 | 99.3% | C15H11ClN2OS | 10MG
SKI II is a small-molecule research inhibitor of sphingosine kinase used to probe SK1 and SK2 activity in biochemical and cellular studies. It is supplied as a white to off-white solid with high purity and is intended for research use only.
- High purity (~99.3% by LCMS) suitable for analytical and biological experiments.
- Inhibits sphingosine kinase with reported IC50 values of ~78 μM (SK1) and ~45 μM (SK2).
- Cell-permeable, enabling use in cell-based assays.
- Stable when stored as recommended: powder at -20°C, in solvent at -80°C.
- Provided with certificate of analysis and safety data for quality and handling information.
Medchemexpress LLC Ly266097 hydrochloride | 172895-39-5 | MFCD00949080 | 99.6% | 407.33 | C21H24Cl2N2O2 | 10 MG
LY266097 hydrochloride is a selective 5-HT2B receptor antagonist supplied as the hydrochloride salt for laboratory research. It is used to study serotonin 5-HT2 receptor pharmacology and is provided at high purity for in vitro and preclinical applications.
- Selective 5-HT2B receptor antagonist.
- Reported pKi values: 5-HT2A 7.7; 5-HT2B 9.8; 5-HT2C 7.6.
- High purity (99.6%) suitable for research use.
- Supplied as a hydrochloride salt in small milligram quantities for laboratory studies.
- Molecular formula C21H24Cl2N2O2; molecular weight 407.33.
![Medchemexpress LLC 3-methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride | 147388-83-8 | MFCD11045960 | 99.4% | 202.68 g·mol⁻¹ | C9H15ClN2O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243190.png-250.jpg)
Medchemexpress LLC 3-methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]isoxazole hydrochloride | 147388-83-8 | MFCD11045960 | 99.4% | 202.68 g·mol⁻¹ | C9H15ClN2O | 1 ML
ABT-418 hydrochloride is a potent, selective agonist of neuronal nicotinic acetylcholine receptors (nAChRs) used in preclinical research to investigate cholinergic signaling, cognition, and anxiolytic mechanisms. It is supplied as a solid and as a ready-to-use 10 mM solution for laboratory applications. CAS 147388-83-8; molecular weight 202.68 g·mol⁻¹. For research use only.
- Potent, selective agonist of neuronal nicotinic acetylcholine receptors.
- Available as solid and as 10 mM solution ready for use.
- High purity suitable for analytical and biological studies.
- Stable under recommended storage conditions.
- Intended for laboratory research use only.
Apexbio Technology LLC BIOTIN-4-AMINOPHENOL-5MG
Biotin-4-aminophenol (CAS No 901770-40-9) is a chemical compound used in biomedical research originating from the field of biochemistry It operates primarily through biotinylation affecting pathways involved in cellular signaling and transport In vitro it demonstrates activity in the nanomolar to low micromolar range making it suitable for precise biological studies Typical applications include experiments in various cell models animal studies and drug screening processes where it serves as a critical reagent for labeling and tracking molecules Experimental concentrations typically depend on the specific research design allowing researchers to tailor its use to their particular study needs