Aminophenols
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Medchemexpress LLC Ly266097 hydrochloride | 172895-39-5 | MFCD00949080 | 99.6% | 407.33 | C21H24Cl2N2O2 | 10 MG
LY266097 hydrochloride is a selective 5-HT2B receptor antagonist supplied as the hydrochloride salt for laboratory research. It is used to study serotonin 5-HT2 receptor pharmacology and is provided at high purity for in vitro and preclinical applications.
- Selective 5-HT2B receptor antagonist.
- Reported pKi values: 5-HT2A 7.7; 5-HT2B 9.8; 5-HT2C 7.6.
- High purity (99.6%) suitable for research use.
- Supplied as a hydrochloride salt in small milligram quantities for laboratory studies.
- Molecular formula C21H24Cl2N2O2; molecular weight 407.33.
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Medchemexpress LLC Mepazine hydrochloride | 2975-36-2 | >98.0% | 10MM 1ML
Mepazine hydrochloride | 2975-36-2 | >98.0% | 10MM 1ML
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Medchemexpress LLC S-14506 hydrochloride | 286369-38-8 | 99.9% | 443.94 | 10 MG
S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also exhibits dopamine antagonist properties by blocking dopamine D2 receptors, inhibiting the in vivo binding of [3H]raclopride in the striatum and olfactory bulbs. This compound has potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Exhibits dopamine antagonist properties by blocking dopamine D2 receptors
- Inhibits in vivo binding of [3H]raclopride
- Potential for anxiolytic agent research
- High affinity for G protein-uncoupled state of 5-HT receptor in HeLa cells
- Dose-dependently antagonizes apomorphine-induced stereotyped climbing and sniffing in mice
- Active in the forced swimming test in rats, inducing immobility
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