Cresols
BIOHIPPO h/m ACSL4-sh-RFP-Puro
h/m ACSL4-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m ACSL4 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse acyl-CoA synthetase long chain family member 4 (ACSL4) The shRNA has been validated to meet or exceed 70% knockdown of ACSL4 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Apexbio Technology LLC EZ Cap Mouse CD252(OX40L) mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse CD252 mRNA encodes cytokine OX40 ligand (OX40L) expressed on the surface of activated antigen-presenting cells such as dendritic cells B cells and macrophages Binding to the OX40 receptor (CD134) the CD252-OX40 signaling pathway plays a key role in the immune system promoting T cell proliferation survival and effector functions This signaling pathway significantly influences immune response regulation immune tolerance maintenance and anti-tumor immunity CD252 is involved in the pathological processes of autoimmune diseases and chronic inflammation EZ Cap Mouse CD252 (OX40L) mRNA (m1 HA tag) is provided at 1 mg/mL It expresses mouse-derived CD137 cytokine tagged with HA facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
STA Pharmaceutical Fmoc-L-3,4-Dimethylphe | 5 g | CAS 1217620-19-3 | MDL MFCD08458428
Fmoc-L-3,4-Dimethylphe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1217620-19-3
- MDL: MFCD08458428
- InChIKey: QMHIEEWTOGXGNA-DEOSSOPVSA-N
- Molecular Weight: 415.489
- Molecular Formula: C26H25NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethylphenyl)propanoic acid
- SMILES: O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](CC4=CC=C(C)C(C)=C4)C(O)=O
Aobchem 2-Chloro-3 5-dimethylphenol | ≥97% | CAS 5538-41-0 | C8H9ClO | 250mg
2-Chloro-3 5-dimethylphenol | ≥97% | CAS 5538-41-0 | C8H9ClO | 250mg
Aobchem 4-Methoxy-2 6-dimethylphenol | ≥97% | CAS 2431-91-6 | C9H12O2 | 250mg
4-Methoxy-2 6-dimethylphenol | ≥97% | CAS 2431-91-6 | C9H12O2 | 250mg
Medchemexpress LLC 4H-1-Benzopyran-4-one, 6-methyl-2-(4-morpholinyl)-8-[1-(phenylamino)ethyl]- | 901398-68-3 | 99.05% | 364.44 | 10 MG
PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor. It is suitable for research applications, particularly in studies involving PI3Kbeta-mediated Akt phosphorylation and mTORC2-mediated Akt phosphorylation.
- Inhibits human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue with an IC50 of 3 nM.
- Inhibits human PI3Kbeta-mediated Akt phosphorylation at T308 residue with an IC50 of 3 nM.
- Inhibits mTORC2-mediated Akt phosphorylation at Ser473 residue with an IC50 of 3 nM.
- Blocks phosphorylation of PKB/Akt at concentrations of 0.1-10 μM.
- Soluble in DMSO at 50 mg/mL.
- Clear solution with 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline at ≥ 2.08 mg/mL.
- Clear solution with 10% DMSO, 90% (20% SBE-β-CD in Saline) at ≥ 2.08 mg/mL.
- Clear solution with 10% DMSO, 90% Corn Oil at ≥ 2.08 mg/mL.
STA Pharmaceutical Fmoc-L-2,4-Dimethylphe | 5 g | CAS 1217728-65-8 | MDL MFCD06659141
Fmoc-L-2,4-Dimethylphe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1217728-65-8
- MDL: MFCD06659141
- InChIKey: MXBSNHLSKRVUBF-DEOSSOPVSA-N
- Molecular Weight: 415.489
- Molecular Formula: C26H25NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dimethylphenyl)propanoic acid
- SMILES: CC1=CC(C)=C(C=C1)C[C@@H](C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O
eMolecules 22061-78-5 | 2-Bromo-3-methylphenol | Ambeed | MFCD09991797 | 187.036 | C7H7BrO | 98.000 | Cc1cccc(O)c1Br | 100mg | 518522859
2-Bromo-3-methylphenol | Ambeed | 22061-78-5 | MFCD09991797 | 187.036 | C7H7BrO | 98.000 | Cc1cccc(O)c1Br | 100mg | 518522859
Apexbio Technology LLC EZ Cap Mouse IL-23 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-23 mRNA (Interleukin-23) encodes IL-12 cytokine It consists of two subunits IL-23 p19 and IL-12 p40 IL-23 binds to its specific receptor IL-23R activating downstream signaling pathways including the JAK-STAT pathway thus promoting inflammatory responses IL-23 is a potential therapeutic target for various diseases including psoriasis Crohn s disease and multiple sclerosis In recent years biological agents targeting IL-23 such as monoclonal antibodies have been developed for clinical application showing good efficacy and safety EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Selleck Chemical LLC Rebaudioside M S3282-1mg
Rebaudioside M isolated from Stevia rebaudiana Bertoni is a natural non-caloric potential sweetener in food and beverage products
eMolecules 412925-16-7 | 3-Amino-3-(3,4-dimethylphenyl)propanoic acid | Combi-Blocks | MFCD02663197 | 193.246 | C11H15NO2 | 97.000 | Cc1ccc(cc1C)C(N)CC(O)=O | 1g | 517026543
3-Amino-3-(3,4-dimethylphenyl)propanoic acid | Combi-Blocks | 412925-16-7 | MFCD02663197 | 193.246 | C11H15NO2 | 97.000 | Cc1ccc(cc1C)C(N)CC(O)=O | 1g | 517026543
BIOHIPPO h/m KRT10-sh-RFP-Puro
h/m KRT10-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m keratin 10 (KRT10) shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse keratin 10 (KRT10) The shRNA has been validated to meet or exceed 70% KRT10 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m EGFR-sh-Puro
h/m EGFR-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m EGFR shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse epidermal growth factor receptor (EGFR) The shRNA has been validated to meet or exceed 70% knockdown of EGFR using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs