Cresols
Medchemexpress LLC Animal-Free FGF-2 Protein, Mouse (His) | 96% | Approximately 19 kDa | 2 UG
FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. It also acts as a mitotic promoter, accelerating cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. This product is for cell culture use only.
- Consists of 144 amino acids
- Produced by E. coli with tag-free protein
- Offers high consistency and stability
- Does not use or contact any animal-derived materials and reagents
Apexbio Technology LLC EZ Cap Mouse IL-12 mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse IL-12 mRNA encodes a cytokine Interleukin-12 secreted by antigen-presenting cells such as dendritic cells macrophages and B cells It promotes the activation and proliferation of T cells and natural killer (NK) cells thus enhancing the body s immune response IL-12 induces the differentiation of T cells into Th1 cells thereby enhancing cell-mediated immunity and increasing the production of interferon- (IFN- ) crucial for antiviral and antitumor immune responses EZ Cap Mouse IL-12 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-12 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
BIOHIPPO h/m SREBP2-sh-RFP-Puro
h/m SREBP2-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m SREBP2 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse sterol regulatory element binding transcription factor 2 (SREBP2/SREBF2) The shRNA has been validated to meet or exceed 70% knockdown of SREBP2 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Apexbio Technology LLC Cytochrome c fragment (93-108) 1mg
Cytochrome c fragment 93-108 is a peptide derived from cytochrome c a mitochondrial protein involved in apoptosis It is designed to interact with apoptotic protease activating factor-1 (Apaf-1) thereby promoting the assembly of the Apaf-1/caspase-9 apoptosome complex and regulating the caspase activation pathway Cytochrome c fragment 93-108 exerts its biological activity primarily through activation of the caspase cascade specifically the activation of caspase-9 and subsequent caspase-3 Based on these pharmacological properties cytochrome c fragment 93-108 holds research potential in studies of apoptosis-related signaling networks caspase activation pathways and drug screening targeting apoptosis regulators
Medchemexpress LLC M-PEG17-acid | 2346581-96-0 | 98.5% | C36H72O19 | 100 MG
m-PEG17-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules employ the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system.
Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Medchemexpress LLC NH-bis(m-PEG8) | 2055013-64-2 | C34H71NO16 | 25 MG
NH-bis(m-PEG8) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 1309241-34-6 | (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone | 100mg
Ambeed | 44-Dihexyl-4H-cyclopenta[12-b54-b]dithiophene | 100mg | 633657988 | A181089 | 153312-86-8 | MFCD27923054 | 346.590 | C21H30S2
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Medchemexpress LLC M-PEG37-acid | 2924199-92-6 | N/A | >96.0% | C76H152O39 | 10MG
m-PEG37-acid is a carboxyl-terminated methoxy-polyethylene glycol (mPEG) linker with an average chain length of approximately 37 ethylene glycol units. It is designed for use as a PEG-based PROTAC linker or spacer in medicinal chemistry and bioconjugation workflows, providing hydrophilicity and flexible spacing between binding motifs while offering a reactive carboxyl terminus for conjugation.
- Carboxyl-terminated mPEG linker with ~37 ethylene glycol units.
- Enhances solubility and hydrophilicity of conjugates.
- Provides flexible spacer for PROTAC synthesis and bioconjugation.
- Terminal carboxyl enables standard amide or ester coupling reactions.
- Reported purity greater than 96% for research applications.
Cambridge Isotope Laboratories 1 2 3 7 8-PentaCDF (unlabeled) 25 ng/mL in nonane 0 1 mL
1 2 3 7 8-PentaCDF (unlabeled) 25 ng/mL in nonane 0 1 mL
Medchemexpress LLC Metalaxyl-M | 70630-17-0 | 98.1% | 10 MM * 1 ML
Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase. It exhibits fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. It can also be utilized to induce inflammation in hepatocytes, regulate tryptophan metabolism, and for ecotoxicology studies.
- Orally active
- Selective inhibitor of fungal RNA polymerase
- Exhibits fungicidal activity
- Interferes with fungal ribosomal RNA synthesis
- Induces inflammation in hepatocytes
- Regulates tryptophan metabolism
- Used for ecotoxicology studies