Cresols
![Medchemexpress LLC 2-[(4-amino-1-tert-butylpyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenol | 833481-73-5 | MFCD28120704 | 99.7% | 297.35 g/mol | C16H19N5O | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248369.png-250.jpg)
Medchemexpress LLC 2-[(4-amino-1-tert-butylpyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenol | 833481-73-5 | MFCD28120704 | 99.7% | 297.35 g/mol | C16H19N5O | 100 MG
2OH-BNPP1 is a small-molecule inhibitor of BUB1 kinase used for research into cell-cycle regulation and cancer-related kinase pathways. The compound is supplied as a white to off-white solid and is intended for in vitro biochemical and cellular assays.
- Inhibits BUB1 serine/threonine kinase for studies of mitotic checkpoint signaling.
- High purity (99.7%) appropriate for research applications.
- Molecular formula C16H19N5O; molecular weight 297.35 g/mol.
- Soluble in DMSO at ≥100 mg/mL; ultrasonic assistance recommended.
- Supplied as a 100 mg solid and should be stored frozen for long-term stability.
- For research use only; not for human or clinical use.
Medchemexpress LLC m-PEG-azide | 98.0% | 500 MG
m-PEG-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with Azide group
- Enables CuAAc reactions with Alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups
- Utilizes ubiquitin-proteasome system for selective protein degradation
- White to off-white solid
- For research use only
BIOHIPPO h/m FGF17-sh-Puro
h/m FGF17-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FGF17 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fibroblast growth factor 17 (FGF17) The shRNA has been validated to meet or exceed 70% knockdown of FGF17 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m MCL1-sh-Puro
h/m MCL1-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human/mouse MCL1 shRNA lentivirus High-titer shRNA lentiviral particles specific for human/mouse MCL1 apoptosis regulator BCL2 family member (MCL1) The shRNA has been validated to meet or exceed 70% MCL1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m FASN-sh-RFP-Puro
h/m FASN-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m IGFBP2 shRNA Set GFP Puro
h/m IGFBP2 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated IGFBP2 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse insulin like growth factor binding protein 2 (IGFBP2) The shRNA has been validated to meet or exceed 70% IGFBP2 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC M-CSF Cynomolgus/Rh 50ug
The M-CSF protein regulates hematopoietic precursor cells promoting their survival proliferation and differentiation M-CSF Protein Cynomolgus/Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque cynomolgus-derived M-CSF protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC Complement C3/C3a M 1mg | 1mg
Complement C3/C3a protein activates the complement system playing a central role in both classical and alternative pathways C3b binds covalently to cell surface carbohydrates or immune aggregates while C3a acts as an inflammatory mediator inducing neutrophil chemoattraction and promoting smooth muscle contraction increased vascular permeability and histamine release The shorter isoform of C3a stimulates B-cells Complement C3/C3a Protein Mouse is the recombinant mouse-derived Complement C3/C3a protein expressed by E coli with tag free
BIOHIPPO h/m ACSL4-sh-GFP/Luc
h/m ACSL4-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m ACSL4 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse acyl-CoA synthetase long chain family member 4 (ACSL4) The shRNA has been validated to meet or exceed 70% knockdown of ACSL4 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
TARGETMOL CHEMICALS INC JERVINE 10MG
Also available in 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed. purity: 99%
eMolecules 609-22-3 | 2,4-Dibromo-6-methylphenol | Combi-Blocks | MFCD00152390 | 265.932 | C7H6Br2O | 98.000 | Cc1cc(Br)cc(Br)c1O | 1g | 232309014
2,4-Dibromo-6-methylphenol | Combi-Blocks | 609-22-3 | MFCD00152390 | 265.932 | C7H6Br2O | 98.000 | Cc1cc(Br)cc(Br)c1O | 1g | 232309014
Medchemexpress LLC TL02-59 | 1315330-17-6 | 99.9% | 609.64 | 1 ML
TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. It inhibits Lyn and Hck, and potently suppresses acute myelogenous leukemia (AML) cell growth.
- Orally active and selective Src-family kinase Fgr inhibitor
- Inhibits Lyn and Hck
- Potently suppresses acute myelogenous leukemia (AML) cell growth
Sigma Aldrich Fine Chemicals Biosciences 2-Methoxy-4-methylphenol natural, 97%, FG | 93-51-6 | MFCD00002378 |
2-Methoxy-4-methylphenol natural, 97%, FG | Purity: 97% | Mol Wt: 138.16 | 93-51-6 | MFCD00002378 |