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Filtered Search Results
Medchemexpress LLC E3 ligase ligand 32 | 2300099-98-1 | MFCD34595287 | 99.9% | 338.16 | C13H12BrN3O3 | 25 G
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E3 ligase Ligand 32 is a small-molecule ligand for E3 ubiquitin ligases designed as a building block for PROTAC (proteolysis-targeting chimera) synthesis. The compound is provided as a solid with high analytical purity and is characterized by CAS 2300099-98-1, molecular formula C13H12BrN3O3, and molecular weight 338.16. Manufacturer documentation includes handling, storage, and purity information suitable for research use.
- Can be used to synthesize PROTAC degraders and link to target ligands.
- High purity suitable for research and synthesis applications.
- Supplied as an off-white to light brown solid for ease of handling.
- Available in multiple package sizes including gram-scale quantities.
- Stable when stored under recommended conditions for extended periods.
- Characterized by CAS and molecular data for unambiguous identification.
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Medchemexpress LLC NPS-1034 | 1221713-92-3 | 98.0% | 551.54 | C31H23F2N5O3 | 10 MG
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NPS-1034 is a small-molecule dual inhibitor of the receptor tyrosine kinases AXL and MET. It exhibits IC50 values of 10.3 nM (AXL) and 48 nM (MET) and is supplied for research use as a solid powder or as a 10 mM solution in DMSO.
- Dual inhibition of AXL and MET with low-nanomolar potency.
- High purity (98.0%) suitable for biochemical and cellular assays.
- Available as solid powder or DMSO solution for assay flexibility.
- Supplied in multiple package sizes to fit experimental needs.
- Useful for studying MET/AXL signaling and drug resistance mechanisms.
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Medchemexpress LLC Atesidorsen sodium | 1MG
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Atesidorsen sodium | 1MG
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Medchemexpress LLC Betaine (Trimethylglycine) | 107-43-7 | 100.0% | 25 G
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Betaine (Trimethylglycine) is a natural compound and active methyl-donor, maintaining normal DNA methylation patterns. Ubiquitous in plants, animals, and microorganisms, it functions as an osmolyte, balancing cellular water and ions. This promotes intestinal microbes against osmotic variations, enhancing fermentation activity.
- Purity of 99.97%
- Appears as a solid
- Color is white to off-white
- Initial source includes endogenous metabolites, disease markers, cancer, plants, animals, and microorganisms
- Structure classified as others
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Medchemexpress LLC Melamine | 108-78-1 | MFCD6055 | 100.0% | 126.12 g/mol | C3H6N6 | 500g
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Melamine is an orally active inducer of Apoptosis Melamine induces animal disease models Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function Melamine also has neurotoxicity and nephrotoxicity Melamine induces cognitive impairment and acute kidney injury models Melamine can also be used to induce bladder cancer and urinary stone models[1][2][3][4][5][6]
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Medchemexpress LLC DBU (1,8-Diazabicyclo[5.4.0]undec-7-ene) | 6674-22-2 | 99.8% | 152.24 | 500 G
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DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic, sterically hindered amidine with strong basicity, possessing multiple properties such as nucleophilicity and coordination ability. It is prone to hydrolysis and can undergo addition, substitution, cyclization, and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst.
- Strong basicity
- Possesses nucleophilicity and coordination ability
- Prone to hydrolysis
- Can undergo addition, substitution, and cyclization reactions
- Can be used as a catalyst
- Derivatives may exhibit fluorescence and anticancer properties
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Medchemexpress LLC Polyethylene glycol 800 | 25322-68-3 | MFCD00081839 | 99.9% | 800.00 | (C2H4O)nH2O | 100g
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PEG800 (Polyethylene glycol 800) is a nonionic surfactant that is soluble in water and many polar solvents[1]
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Medchemexpress LLC Bis(pinacolato)diborane | 73183-34-3 | 99.97% | C12H24B2O4 | 10 G
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Bis(pinacolato)diborane is an organoboron reagent that serves as a source of the [Bpin] moiety with pronounced nucleophilic character. It is used in the synthesis of various organoboranes, including organoboron compounds and arylboronates. This white to off-white solid reacts with p-benzyne to produce tetraborylated products and can tetraborate p-benzoyne generated from 1,2-diethynylbenzene derivatives for in vitro applications. It is recommended for research use only.
- Serves as a source of the [Bpin] moiety with pronounced nucleophilic character.
- Used in the synthesis of various organoboranes, including organoboron compounds and arylboronates.
- Reacts with p-benzyne to produce tetraborylated products.
- Can tetraborate p-benzoyne generated from 1,2-diethynylbenzene derivatives for in vitro applications.
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Medchemexpress LLC CVT-313 (Cdk2 Inhibitor III) | 199986-75-9 | MFCD06411412 | C20H28N6O3 | 1 ML
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CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2. It has an IC50 of 0.5 μM for CDK2 and inhibits CDC5L phosphorylation. This compound shows significant effects on cell proliferation at concentrations ranging from 5-20 μM, with high selectivity against nonrelated ATP-dependent serine/threonine kinases.
- Potent and selective CDK2 inhibitor
- Reversible and ATP-competitive
- Inhibits CDC5L phosphorylation
- Active in cell proliferation assays
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Medchemexpress LLC Proglumide sodium | 99247-33-3 | MFCD00069301 | 99.6% | 356.39 g·mol⁻¹ | C18H25N2NaO4 | 1 ML
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Proglumide sodium is the sodium salt of proglumide, a nonpeptide cholecystokinin (CCK) A/B receptor antagonist used as a research reagent. Supplied as an aqueous solution at 10 mM concentration in a 1 mL vial, it is intended for in vitro research and receptor pharmacology studies.
- Ready-to-use 10 mM aqueous solution.
- Supplied in a 1 mL vial for small-volume assays.
- Molecular weight 356.39 g·mol⁻¹.
- Molecular formula C18H25N2NaO4.
- Reported purity 99.6% suitable for research applications.
- Useful for CCK-A/B receptor modulation and related pharmacology studies.
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Medchemexpress LLC Tstu | 105832-38-0 | ≥99.0% | 301.05 | 500 G
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TSTU is a coupling reagent utilized in peptide chemistry. It facilitates the conversion of carboxylic acids into their corresponding N-hydroxysuccinimidyl (NHS) esters. It can be used for attaching labels to peptides, proteins, and other similar molecules.
- Facilitates conversion of carboxylic acids to NHS esters.
- Suitable for attaching labels to peptides and proteins.
- Applicable for in situ formation of succinimide esters.
- Functions in mixed aqueous/organic media for amide bond formation.
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Medchemexpress LLC Tetramethylfluoroformamidinium (hexafluorophosphate) | 164298-23-1 | 97.0% | 264.12 | 100 G
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Tetramethylfluoroformamidinium (hexafluorophosphate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Can be used as a biological material or organic compound
- Suitable for life science related research
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Medchemexpress LLC 5H-Dibenz[b,f]azepine, 10,11-dihydro- | 494-19-9 | 99.98% | 25 G
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Iminodibenzyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It serves as an intermediate for the antiepileptic agent Carbamazepine and has been shown to inhibit the 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells. This product is intended for research use only.
- Suitable for life science research
- Used as an intermediate for antiepileptic agent Carbamazepine
- Inhibits 5-lipoxygenase pathway in RBL-1 cells
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Medchemexpress LLC Neutral Red (IND) | 553-24-2 | 96.3% | 100 G
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Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.
- Stains living cells, secreted proteins and other molecular structures.
- Wide range of applications in cell imaging and staining.
- Used in industrial fields such as water treatment, food processing and paper manufacturing as an indicator or colorant.
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Medchemexpress LLC Phospho-Rb2 p130 (Ser952) antibody (YA1034) | 100 UL
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The Phospho-Rb2 p130 (Ser952) Antibody (YA1034) is a laboratory chemical designed for research use. It has a predicted and observed molecular weight of 128 kDa.
- Stable under recommended storage conditions
- Suitable for laboratory chemicals and manufacture of substances
- For research use only
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