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Filtered Search Results
Medchemexpress LLC Perospirone (hydrochloride) | 129273-38-7 | 99.9% | 25 MG
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Perospirone hydrochloride (SM-9018) is an orally active antagonist of the 5-HT2A receptor (Ki of 0.6 nM) and dopamine D2 receptor (Ki of 1.4 nM). It also acts as a partial agonist of the 5-HT1A receptor (Ki of 2.9 nM). This compound is classified as an atypical antipsychotic agent and is being investigated for its potential in schizophrenic disease research.
- Orally active 5-HT2A receptor antagonist (Ki of 0.6 nM)
- Dopamine D2 receptor antagonist (Ki of 1.4 nM)
- Partial agonist of the 5-HT1A receptor (Ki of 2.9 nM)
- Atypical antipsychotic agent
- Potential for schizophrenic disease research
- Targets 5-HT1 Receptor (Ki: 18 nM)
- Targets D1 Receptor (Ki: 41 nM)
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Medchemexpress LLC Milnacipran hydrochloride | 101152-94-7 | 99.7% | 25 MG
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Milnacipran hydrochloride is an orally active Serotonin and Norepinephrine reuptake inhibitor. It inhibits monoamine transporters, specifically the norepinephrine transporter and the serotonin transporter, with Ki values of 31 and 8.5 nM, respectively. It also inhibits pERK1/2 activation. Milnacipran hydrochloride exhibits antidepressant, anxiolytic, and analgesic properties and can inhibit biting behavior in mice. It is used in the study of major depressive disorder, anxiety disorders, and neuropathic pain, such as fibromyalgia.
- Orally active serotonin and norepinephrine reuptake inhibitor
- Inhibits monoamine transporters with Ki values of 31 and 8.5 nM
- Inhibits pERK1/2 activation
- Exhibits antidepressant, anxiolytic, and analgesic properties
- Can inhibit biting behavior in mice
- Used in studies for major depressive disorder, anxiety disorders, and neuropathic pain
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Medchemexpress LLC L-ornithine hydrochloride | 3184-13-2 | MFCD00064562 | 99.9% | 168.62 g·mol⁻1 | C5H13ClN2O2 | 500 MG
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L-ornithine hydrochloride is a research-grade, non-proteinogenic amino acid used in studies of nitrogen metabolism and the urea cycle. Supplied as a white to off-white solid, the material is provided with batch-specific quality documentation for laboratory and analytical use.
- High purity (~99.9%) for research and analytical applications.
- Used in urea cycle and nitrogen metabolism studies.
- White to off-white solid, facile handling and weighing.
- Available in small laboratory sizes, including 500 mg.
- Provided with batch-specific certificate of analysis for traceability.
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Medchemexpress LLC Saxagliptin (hydrochloride) | 709031-78-7 | 99.7% | 351.87 | 25 MG
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor with a Ki of 0.6-1.3 nM. This compound has potential for research into type 2 diabetes mellitus.
- Potent inhibitor of dipeptidyl peptidase-4 (DPP-4).
- Selective and reversible action.
- Orally active compound.
- Increases β-cell proliferation.
- Increases p-AKT and active β-catenin protein levels.
- Increases c-myc and cyclin D1 protein expression.
- Prevents degradation of glucagon-like peptide-1.
- Increases secretion of insulin.
- Decreases secretion of glucagon.
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Medchemexpress LLC 3-methoxytyramine hydrochloride | 1477-68-5 | MFCD00012902 | >95.0% | 203.67 | C9H14ClNO2 | 500 MG
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3-Methoxytyramine hydrochloride is a dopamine metabolite used in research that can activate trace amine-associated receptor 1 (TAAR1). Provided as a research-grade analytical standard, it is intended for laboratory applications and should be stored sealed, away from moisture and light, under low-temperature conditions to preserve stability.
- acts as a biochemical standard and dopamine metabolite for research applications.
- reported to activate trace amine-associated receptor 1 (TAAR1) for pharmacological studies.
- molecular formula C9H14ClNO2 and molecular weight 203.67 support analytical identification.
- recommended storage sealed and refrigerated or frozen to maintain stability.
- solubility data provided for preparing stock solutions at common concentrations.
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Medchemexpress LLC Saxagliptin (hydrochloride) | 709031-78-7 | 99.71% | 351.87 | 1 ML
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It has the potential for research in type 2 diabetes mellitus.
- It acts by preventing the degradation of glucagon-like peptide-1, which increases insulin secretion and decreases glucagon secretion.
- Studies have shown that saxagliptin can induce β-cell proliferation.
- It has been observed to increase p-AKT and active β-catenin protein levels, alongside increased c-myc and cyclin D1 protein expression.
- It dose-dependently inhibits plasma DPP-4 activity.
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Medchemexpress LLC Galidesivir hydrochloride | 222631-44-9 | 99.9% | 301.73 | 50 MG
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Galidesivir hydrochloride | 222631-44-9 | 99.9% | 301.73 | 50 MG
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eMolecules Ambeed / 3-Fluoro-4-hydroxybenzonitrile / 5g / 490560435 / A411028 / / 405-04-9 / MFCD00215834 / 137.113 / C7H4FNO
Ambeed / 3-Fluoro-4-hydroxybenzonitrile / 5g / 490560435 / A411028 / / 405-04-9 / MFCD00215834 / 137.113 / C7H4FNO
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Medchemexpress LLC PF-06815345 hydrochloride | 2334434-49-8 | 98.2% | 634.49 g/mol | C27H30Cl2FN9O4 | 5 MG
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PF-06815345 hydrochloride is a small-molecule, orally active inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) provided for research use. It shows in vitro PCSK9 inhibition (IC50 13.4 μM) and reduces PCSK9 levels in vivo in mice. The compound is supplied as the hydrochloride salt, formula C27H30Cl2FN9O4, molecular weight 634.49 g/mol.
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Medchemexpress LLC (R)-3-hydroxybutanoic acid sodium | 13613-65-5 | MFCD00077788 | 99.9% | 126.09 | C4H7NaO3 | 10 G
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(R)-3-Hydroxybutanoic acid sodium is the sodium salt of the endogenous metabolite R-3-hydroxybutyric acid supplied as a white to off-white solid for research applications. It has formula C4H7NaO3 and molecular weight 126.09. Reported purity is 99.90%. Manufacturer data include detailed solubility and storage guidance suitable for in vitro and in vivo use.
- High stated purity (99.90%).
- White to off-white solid suitable for analytical and formulation workflows.
- High aqueous solubility: 100 mg/mL in water and PBS with ultrasonic assistance.
- DMSO solubility up to 50 mg/mL with ultrasonic warming to 60°C.
- Available in multiple pack sizes, including 10 g, for scaling experiments.
- Recommended storage: sealed, away from moisture; in solvent store at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Agomelatine hydrochloride | 1176316-99-6 | 99.98% | 279.76 | 50 MG
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Agomelatine hydrochloride | 1176316-99-6 | 99.98% | 279.76 | 50 MG
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Medchemexpress LLC 3-Hydroxybenzaldehyde | 100-83-4 | 99.9% | C7H6O2 | 10 G
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3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for various phenolic compounds. It functions as a substrate for aldehyde dehydrogenase (ALDH) in both rats and humans, and is produced by 3-hydroxybenzyl-alcohol dehydrogenase. This compound has demonstrated vasculoprotective effects both in vitro and in vivo, positioning it as a promising subject for atherosclerosis research.
- Inhibits vascular smooth muscle cells proliferation, cell cycle, and cell migration
- Inhibits production levels of p-NF-κB and p-p38 increased by TNF-α in human umbilical vein endothelial cells
- Exhibits anti-thrombic effects in vivo
- Considered for research on atherosclerosis
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Medchemexpress LLC Guretolimod hydrochloride | 00-00-0 | 98.7% | 550.01 | C24H35ClF3N5O4 | 5 MG
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Guretolimod hydrochloride is a synthetic small-molecule Toll-like receptor 7 (TLR7) agonist supplied for research use. It is used in preclinical studies to stimulate innate immune signaling and evaluate immunostimulatory and antitumor responses in vitro and in vivo models.
- Potent TLR7 agonist for immune activation studies.
- Suitable for in vitro and in vivo preclinical research.
- High purity (approximately 98.7%) for consistent results.
- Hydrochloride salt form to improve solubility and handling.
- Characterized chemical identity with molecular formula C24H35ClF3N5O4 and molecular weight 550.01.
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Medchemexpress LLC Miransertib hydrochloride (ARQ-092 hydrochloride) | 1313883-00-9 | 99.7% | 468.98 | 100 MG
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Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective, and allosteric Akt inhibitor. It exhibits specific IC50s for Akt1, Akt2, and Akt3, and is a potent inhibitor of the AKT1-E17K mutant protein. This compound is considered for research into PI3K/AKT-driven tumors, Proteus syndrome, and is effective against Leishmania.
- Potent, orally active, selective, and allosteric Akt inhibitor.
- Exhibits specific IC50s for Akt1, Akt2, and Akt3.
- Inhibits the AKT1-E17K mutant protein.
- Suitable for research in PI3K/AKT-driven tumors and Proteus syndrome.
- Effective against Leishmania.
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Medchemexpress LLC Valnivudine hydrochloride | 956483-03-7 | 98.99% | 534.04 | 50 MG
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Valnivudine hydrochloride (FV-100) is a potent, selective, and orally active anti-varicella zoster virus agent. It is a proagent of CF-1743 and exhibits very low toxicity in vivo. It is intended for research use only.
- Potent, selective, and orally active anti-varicella zoster virus agent.
- Proagent of CF-1743.
- Exhibits very low toxicity in vivo.
- Intensely fluorescent when illuminated by wavelengths of 340-380 nm (In Vitro).
- Does not induce biologically relevant respiratory changes or apparent neuropharmacological effects in rats at 50-500 mg/kg; p.o. (In Vivo).
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