Halophenols

Organic compounds derived from phenols that contain a halogen atom (bromine, chlorine, fluorine, iodine).

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2,866 – 2,880 of 7,340 results

2,866

Apexbio Technology LLC AS-605240 648450-29-7 10mM (in 1mL DMSO)

AS-605240 (CAS 648450-29-7) is a cell-permeable small molecule inhibitor selectively targeting class I phosphoinositide 3-kinases (PI3Ks) with pronounced potency against the PI3K isoform (IC50 0 008 M) and lower activity for PI3K / / (IC50 0 06 0 27 and 0 3 M respectively) Structural studies show that AS-605240 binds to PI3K via interactions with Lys-833 and Val-882 It impairs PI3K/Akt signaling as evidenced by inhibition of C5a-induced PKB phosphorylation in RAW264 macrophages In vivo AS-605240 reduces leukocyte migration and suppresses joint inflammation in mouse models of peritonitis and collagen-induced arthritis highlighting its value for investigating PI3K -mediated immune pathways and inflammatory processes

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2,867

Medchemexpress LLC 6-bromo-3-fluoropyridine-2-carbaldehyde | 885267-36-7 | MFCD07781224 | 99.9% | 204.00 g/mol | C6H3BrFNO | 500 MG

6-bromo-3-fluoropyridine-2-carbaldehyde is a pyridine-derived aldehyde used as a synthetic intermediate in medicinal chemistry research. It is supplied as a solid with high chemical purity and characterized by standard analytical testing.

Used as a synthetic intermediate in medicinal chemistry
Cas number 885267-36-7
Molecular formula C6H3BrFNO
Molecular weight 204.00 g/mol
Purity (GC) 99.92%
Appearance white to light yellow solid
Storage -20°C, sealed and protected from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month
Typical supplied quantity 500 mg

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2,868

Medchemexpress LLC L-selectin/CD62L protein, mouse (HEK293, His) | ≥98.0% | 10 UG

Recombinant mouse L-selectin (CD62L) extracellular domain produced in HEK293 cells with a C-terminal His tag. L-selectin is a calcium-dependent lectin that mediates lymphocyte adhesion to endothelial cells; this purified recombinant protein is provided for immunology, cell-adhesion, and receptor-ligand interaction studies. Certificate of Analysis reports high purity.

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2,869

Apexbio Technology LLC Ticlopidine HCl 53885-35-1 5g

Ticlopidine HCl is a small-molecule inhibitor targeting the platelet P2Y purinergic receptor subtype It is designed to inhibit platelet aggregation by blocking the interaction of extracellular adenosine diphosphate (ADP) with its receptor thereby suppressing ADP-induced signaling pathways essential for platelet activation Ticlopidine HCl exerts its biological activity primarily through selective inhibition of ADP-driven platelet responses It demonstrates inhibitory activity with an IC50 of approximately 2 M Based on these pharmacological properties Ticlopidine HCl holds research potential in studies of platelet activation mechanisms thrombotic disease modeling and evaluation of therapeutic approaches targeting ADP-mediated platelet signaling pathways

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2,870

Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 10mM (in 1mL DMSO)

Chlorprothixene hydrochloride (CAS 6469-93-8) is a small-molecule antagonist targeting dopamine (D1 D2 D3 D5) and histamine H1 receptors It modulates neurotransmission by blocking these receptors thereby regulating dopaminergic and histaminergic pathways Chlorprothixene hydrochloride exerts its biological activity primarily through receptor antagonism In in vitro studies it demonstrates nanomolar affinity with Ki values of 18 nM (D1) 2 96 nM (D2) 4 56 nM (D3) 9 nM (D5) and 3 75 nM (H1) Additionally it reduces SARS-CoV viral replication (IC50 13 0 18 5 M depending on strain) Based on these pharmacological properties chlorprothixene hydrochloride holds research potential in antipsychotic therapy antiviral investigation and modulation of inflammation in cystic fibrosis models

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2,871

Medchemexpress LLC 2-piperidinone, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl] | 870843-42-8 | 97.0% | 419.49 | C25H26FN3O2 | 1 ML

E 2012 is a small-molecule γ-secretase modulator used in preclinical research to reduce amyloid β-42 and to probe cholesterol biosynthesis via DHCR24 inhibition. Supplied for laboratory use as a concentrated solution in DMSO, it is intended for in vitro and related studies.

Potent γ-secretase modulator activity.
Reduces amyloid β-42 levels in cellular assays.
Inhibits 3β-hydroxysterol Δ24-reductase (DHCR24).
Available as a 10 mM solution in DMSO (1 mL) and as solid formats.
High solubility in DMSO (~119 mM) with ultrasonic assistance.
Manufacturer-reported purity approximately 97.0% and defined storage conditions.

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2,872

eMolecules Key Organics/BIONET Esmolol HCl 1mg 564364906 KS-1353 97 000 81161-17-3 MFCD00941432 331 840 C16H26ClNO4

Key Organics/BIONET Esmolol HCl 1mg 564364906 KS-1353 97 000 81161-17-3 MFCD00941432 331 840 C16H26ClNO4

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2,873

Medchemexpress LLC E3 ligase Ligand 64 | 2760850-50-6 | ≥98.0% | C₁₂H₁₀BrFN₄O₂ | 25 G

E3 ligase Ligand 64 is a ligand for E3 ligase, used for the synthesis of RP03707. This product is a solid with a molecular weight of 341.14 and a chemical formula of C₁₂H₁₀BrFN₄O₂. It is intended for laboratory research use only and should be handled by qualified scientists in appropriately equipped facilities. It is classified with several hazards, including acute oral toxicity, skin and eye irritation, and potential respiratory irritation.

Identified as 2,4(1H,3H)-Pyrimidinedione, 1-(6-bromo-5-fluoro-1-methyl-1H-indazol-3-yl)dihydro-.
Used for synthesis.
For research use only.
Store at room temperature for 3 years; in solvent at -80°C for 2 years or -20°C for 1 year.
Shipping at room temperature if less than 2 weeks.
Causes skin and serious eye irritation.
May cause respiratory irritation.
Harmful if swallowed.

Pricing & Availability

2,874

Medchemexpress LLC Octenidine dihydrochloride | 70775-75-6 | 99.7% | 1 G

Octenidine dihydrochloride is an effective antiseptic compound for skin, mucous membranes, and wounds. It is for research use only.

Antiseptic compound: effective for skin, mucous membranes, and wounds.
Microbicidal activity: at concentrations less than 1.5 μM (0.94 μg/mL), it causes a greater than 99% reduction of tested microbial populations within 15 minutes.
Broad spectrum: effective against Staphylococcus epidermidis, E. coli, and C. albicans.
In vivo efficacy: maintains antimicrobial activity when applied to the skin of hands and feet.
Dental plaque reduction: daily topical application of 1% solutions significantly reduces plaque score on buccal tooth surfaces.

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2,875

Medchemexpress LLC Acetamide, N-(3-hydroxyphenyl)- | 621-42-1 | 99.97% | 100 G

Metacetamol is a non-hepatotoxic analog of acetaminophen. It increases glutathione in PHH cells and causes mitochondrial damage. It also increases total JNK in PHH cells. This product is for research use only and has not been fully validated for medical applications.

Increases glutathione in PHH
Causes mitochondrial damage
Increases total JNK in PHH cells
Non-hepatotoxic analog of acetaminophen
Appears as an off-white to light brown solid
Store at room temperature for 3 years
When in solvent, store at -80°C for 2 years or -20°C for 1 year
Soluble in DMSO at 50 mg/mL

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2,876

Medchemexpress LLC E-982 | 858102-78-0 | 99.6% | 473.58 | 1 MG

E-982 is a steroid utilized for the on-line screening of the DNA unwinding element binding protein (DUE-B) immobilized protein column.

Supports on-line pharmacological studies
Suitable for research use only

Pricing & Availability

2,877

Medchemexpress LLC N,N'-Dibenzylethylenediamine | 140-28-3 | 99.8% | 240.34 | 5 G

N,N'-Dibenzylethylenediamine forms a chelator with metals and interacts with penicillin to form a stable and tasteless salt of penicillin. It is suitable for various research applications.

Forms a chelator with metals
Interacts with penicillin to form a stable and tasteless salt
Suitable as a biochemical assay reagent
Functions as a chelator

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2,878

eMolecules 2-BROMO-1 10-PHENANTHROLINE 5G

5000211002 2-BROMO-1 10-PHENANTHROLINE 5G

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2,879

eMolecules 2-BROMO-1 10-PHENANTHROLIN 10G

5000211010 2-BROMO-1 10-PHENANTHROLIN 10G

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2,880

eMolecules 1-BROMO-2 2-DIMETHOXYPROPA 25G

5000211013 1-BROMO-2 2-DIMETHOXYPROPA 25G

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Halophenols

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Apexbio Technology LLC AS-605240 648450-29-7 10mM (in 1mL DMSO) Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 6-bromo-3-fluoropyridine-2-carbaldehyde | 885267-36-7 | MFCD07781224 | 99.9% | 204.00 g/mol | C6H3BrFNO | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC L-selectin/CD62L protein, mouse (HEK293, His) | ≥98.0% | 10 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Ticlopidine HCl 53885-35-1 5g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 10mM (in 1mL DMSO) Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-piperidinone, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl] | 870843-42-8 | 97.0% | 419.49 | C25H26FN3O2 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC E3 ligase Ligand 64 | 2760850-50-6 | ≥98.0% | C₁₂H₁₀BrFN₄O₂ | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octenidine dihydrochloride | 70775-75-6 | 99.7% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Acetamide, N-(3-hydroxyphenyl)- | 621-42-1 | 99.97% | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC E-982 | 858102-78-0 | 99.6% | 473.58 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N,N'-Dibenzylethylenediamine | 140-28-3 | 99.8% | 240.34 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More