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Filtered Search Results
Medchemexpress LLC Desipramine hydrochloride | 58-28-6 | MFCD00058108 | 1 G
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Desipramine hydrochloride acts as an inhibitor for norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT). It exhibits Ki values of 4, 61, and 78,720 nM for NET, SERT, and DAT respectively. Studies have shown that chronic administration can reduce NET expression in a dose-dependent manner.
- Inhibitor of norepinephrine transporter (NET)
- Inhibitor of 5-HT transporter (SERT)
- Inhibitor of dopamine transporter (DAT)
- Reduces norepinephrine transporter expression in a dose-dependent manner
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Medchemexpress LLC Relenopride (hydrochloride) | 1221416-42-7 | 99.9% | 529.43 | 25 MG
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Relenopride (hydrochloride) | 1221416-42-7 | 99.9% | 529.43 | 25 MG
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Medchemexpress LLC Pardoprunox hydrochloride | 269718-83-4 | 99.5% | 269.73 | 25 MG
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Pardoprunox hydrochloride (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist. It demonstrates potent partial agonism at D2 receptors and partial agonism at D3 receptors, while also acting as a full agonist for 5-HT1A receptors.
- Partial dopamine D2 and D3 receptor agonist
- Serotonin 5-HT1A receptor agonist
- Potent partial D2 receptor agonist with 50% efficacy on forskolin stimulated cAMP accumulation
- Partial agonist at human recombinant dopamine D3 receptors, inducing [(35)S]GTPgammaS binding
- Full 5-HT1A receptor agonist on forskolin induced cAMP accumulation
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Medchemexpress LLC Pirarubicin (hydrochloride) | 95343-20-7 | 99.1% | 664.10 | 100 MG
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Pirarubicin Hydrochloride is an anthracycline antibiotic that acts as a topoisomerase II inhibitor and is widely used for the treatment of various cancers, particularly solid tumors. This compound induces autophagy in bladder cancer cells in a dose-dependent manner and also induces apoptosis.
- Acts as a topoisomerase II inhibitor
- Widely used for the treatment of various cancers
- Induces autophagy in bladder cancer cells
- Induces apoptosis by inhibiting mTOR/p70S6K/4E-BP1 pathway
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Medchemexpress LLC Quinagolide hydrochloride | 94424-50-7 | 99.6% | 432.02 | 50 MG
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Quinagolide hydrochloride is a selective and orally active dopamine D2 receptor agonist. It acts as an inhibitor of prolactin and down-regulates AKT levels and its phosphorylation. It shows antitumor effects and can be used for cancer research.
- Selective and orally active dopamine D2 receptor agonist.
- Inhibitor of prolactin.
- Down-regulates AKT levels and its phosphorylation.
- Exhibits antitumor effects.
- Used for cancer research.
- Reduces non-ergot dopamine receptor 2 (DRD2) mRNA expression.
- Inhibits invasive properties of endometrial mesenchymal stromal cells.
- Reduces endothelial differentiation of endometrial mesenchymal stromal cells.
- Effectively inhibits tumor growth in vivo.
- Induces normalization of plasma PRL levels and reduced tumor size.
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Medchemexpress LLC Ziprasidone hydrochloride | 122883-93-6 | 99.7% | C21H22Cl2N4OS | 50 MG
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Ziprasidone hydrochloride is an orally active combined 5-HT and dopamine receptor antagonist.
- Acts as a 5-HT and dopamine receptor antagonist
- Has high affinity for rat D2, 5-HT2A, and 5-HT1A receptors
- Blocks wild-type hERG current
- Affects weight gain, physical activity, and thermogenesis in vivo
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Medchemexpress LLC Smcy HY peptide (738-746) | 207113-06-2 | 1167.34 | 5 MG
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Smcy HY peptide (738-746) is an H2-Dᵇ-restricted peptide corresponding to amino acids 738-746 of the Smcy protein, targeting MHC in the immunology/inflammation pathway. It has a sequence of Lys-Cys-Ser-Arg-Asn-Arg-Gln-Tyr-Leu.
- H2-Dᵇ-restricted peptide
- Corresponds to amino acids 738-746 of Smcy protein
- Targets MHC
- Involved in immunology/inflammation pathway
- Can be stored as powder for up to 2 years at -80°C
- Can be stored in solvent for up to 6 months at -80°C
- Recommended storage conditions are sealed, away from moisture and light, under nitrogen
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Medchemexpress LLC Crinecerfont hydroch 100mg | 321839-75-2 | 100MG
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Crinecerfont (SSR-125543) hydrochloride is a potent orally active non-peptide CRF1 receptor antagonist Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1 Crinecerfont (hydrochloride) is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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Medchemexpress LLC Benzydamine hydrochloride | 132-69-4 | 99.2% | 345.87 | 10 MM 1 ML
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Benzydamine hydrochloride is an orally administered prostaglandin synthesis inhibitor that possesses anti-inflammatory, analgesic, antipyretic, and antibacterial properties. It can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells. This specific product is a 10 mM solution in water, ready for reconstitution.
- Anti-inflammatory, analgesic, antipyretic, and antibacterial properties
- Inhibits TNF-α and stabilizes cell membranes
- Reduces oxidative stress within cells
- Suitable for laboratory centrifugation and storage
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Medchemexpress LLC JNJ-47117096 hydroch | 1610536-69-0 | 50MG
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JNJ-47117096 hydrochloride is potent and selective MELK inhibitor with an IC50 of 23 nM also effectively inhibits Flt3 with an IC50 of 18 nM
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Medchemexpress LLC Mavorixafor hydrochloride | 880549-30-4 | MFCD11977316 | 99.1% | 385.93 g·mol⁻1 | C21H28ClN5 | 10 MG
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Mavorixafor hydrochloride is a potent, selective CXCR4 antagonist supplied as the hydrochloride salt for research use. It is provided as a viscous liquid with high purity and is intended for in vitro and preclinical studies of CXCR4 signaling and related disease models.
- High purity: 99.1%.
- Molecular weight: 385.93 g·mol⁻1.
- Cas number: 880549-30-4.
- Physical form: viscous liquid, light yellow to brown.
- Storage: store at -20 °C, sealed, protect from moisture and light.
- Application: research into CXCR4 biology and WHIM syndrome models.
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Medchemexpress LLC Minodronic acid hydrate | 155648-60-5 | 99.67% | 340.16 | 100 MG
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Minodronic acid hydrate is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. It also acts as an antagonist of purinergic P2X2/3 receptors, which are involved in pain.
- Directly prevents cell proliferation.
- Induces apoptosis in cancer cells.
- Inhibits metastasis of various cancer cell types.
- Antagonizes purinergic P2X2/3 receptors.
- Involved in pain management.
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Medchemexpress LLC Acriflavine hydrochloride | 69235-50-3 | 99.4% | 541.90 | 500 MG
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Acriflavine hydrochloride | 69235-50-3 | 99.4% | 541.90 | 500 MG
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Medchemexpress LLC Minocycline (hydrochloride) | 13614-98-7 | 99.1% | 493.94 | 1 ML
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Minocycline hydrochloride is an orally active, potent, and BBB-penetrated semi-synthetic tetracycline antibiotic. It functions as a hypoxia-inducible factor (HIF)-1α inhibitor and inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome, leading to a bacteriostatic effect. This compound also exhibits anti-cancer, anti-inflammatory, and glutamate antagonist properties.
- Orally active.
- Potent.
- Blood-brain barrier (BBB)-penetrated.
- Functions as a hypoxia-inducible factor (HIF)-1α inhibitor.
- Inhibits bacterial protein synthesis.
- Exhibits bacteriostatic effect.
- Shows anti-cancer effects.
- Demonstrates anti-inflammatory properties.
- Acts as a glutamate antagonist.
- Reduces glutamate neurotransmission.
- Possesses neuroprotective properties.
- Displays antidepressant effects.
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Medchemexpress LLC JNJ-47117096 hydrochloride | 1610536-69-0 | 99.7% | 398.89 g/mol | C21H23ClN4O2 | 100MG
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JNJ-47117096 hydrochloride is a research-grade small-molecule kinase inhibitor supplied as a hydrochloride salt. It potently inhibits maternal embryonic leucine zipper kinase (MELK) and also inhibits Flt3, making it suitable for biochemical and cellular studies of kinase signaling pathways.
- Potent MELK inhibitor (IC50 23 nM).
- Also inhibits Flt3 (IC50 18 nM).
- High purity suitable for research (99.7%).
- Solid white to off-white appearance for easy handling.
- Molecular weight 398.89 g/mol and formula C21H23ClN4O2.
- Available in multiple package sizes from 5 mg to 500 mg.
- For research use only; not for human or clinical use.
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