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Filtered Search Results
Medchemexpress LLC RAVOXERTINIB HYDROCH 50 mg
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RAVOXERTINIB HYDROCH 50MG
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Aobchem 5-Bromo-N N-dimethylpicolinamide | ≥97% | CAS 845305-86-4 | C8H9BrN2O | 25g
5-Bromo-N N-dimethylpicolinamide | ≥97% | CAS 845305-86-4 | C8H9BrN2O | 25g
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Aobchem 4-Bromo-2 6-dimethypyridine | ≥95% | CAS 5093-70-9 | C7H8BrN | 25g
4-Bromo-2 6-dimethypyridine | ≥95% | CAS 5093-70-9 | C7H8BrN | 25g
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Aobchem 8-Bromo-5-chloroquinoline | ≥97% | CAS 1154741-20-4 | C9H5BrClN | 25g
8-Bromo-5-chloroquinoline | ≥97% | CAS 1154741-20-4 | C9H5BrClN | 25g
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Aobchem 3-Bromo-5-chlorobenzonitile | ≥97% | CAS 304854-55-5 | C7H3BrClN | 100g
3-Bromo-5-chlorobenzonitile | ≥97% | CAS 304854-55-5 | C7H3BrClN | 100g
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Aobchem 2-Bromo-1-methoxy-4-(methoxymethoxy)benzene | ≥95% | CAS 2158298-51-0 | C9H11BrO3 | 10g
2-Bromo-1-methoxy-4-(methoxymethoxy)benzene | ≥95% | CAS 2158298-51-0 | C9H11BrO3 | 10g
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Aobchem 2-Bromo-5-methoxy-N N-diethylbenzylamine | ≥97% | CAS 1394291-48-5 | C12H18BrNO | 10g
2-Bromo-5-methoxy-N N-diethylbenzylamine | ≥97% | CAS 1394291-48-5 | C12H18BrNO | 10g
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Aobchem 4-Bromo-2 6-dimethylfluorobenzene | ≥97% | CAS 99725-44-7 | C8H8BrF | 25g
4-Bromo-2 6-dimethylfluorobenzene | ≥97% | CAS 99725-44-7 | C8H8BrF | 25g
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Aobchem 3-Bromo-2-fluorobenzaldehyde | ≥97% | CAS 149947-15-9 | C7H4BrFO | 100g
3-Bromo-2-fluorobenzaldehyde | ≥97% | CAS 149947-15-9 | C7H4BrFO | 100g
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Medchemexpress LLC Relenopride hydrochloride | 1221416-42-7 | 99.9% | 529.43 | 1 ML
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Relenopride hydrochloride is a specific and selective 5-HT4 receptor agonist, with a Ki of 4.96 nM. It exhibits significantly lower affinity for 5-HT2A and 5-HT2B receptors compared to 5-HT4. This compound is known to increase gastrointestinal (GI) motility.
- Specific and selective 5-HT4 receptor agonist
- Increases gastrointestinal (GI) motility
- Exhibits lower affinity for 5-HT2A and 5-HT2B receptors
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Medchemexpress LLC 7-MAD-MDCPT HYDROCH 1 mg
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7-MAD-MDCPT HYDROCH 1MG
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Medchemexpress LLC LEVOMEDETOMIDINE HY 50 mg
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LEVOMEDETOMIDINE HY 50MG
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Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.3% | 413.71 | 1 MG
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ML-00253764 hydrochloride is a brain penetrant, nonpeptidic melanocortin receptor 4 (MC4R) antagonist with Ki and IC50 values of 0.16 μM and 0.103 μM, respectively. It is capable of crossing the blood-brain barrier.
- Target: melanocortin receptor 4 (MC4R) antagonist.
- Brain penetrant: can cross the blood-brain barrier.
- In vitro activity: displaces NDP-α-MSH binding with a mean IC50 of 0.32 μM for hMC4-R, 0.81 μM for hMC3-R, and 2.12 μM for hMC5-R. At 100 μM, it decreases cAMP production induced by [NLE4,D-Phe7]-α-melanocyte stimulating hormone ([NDP]-α-MSH) by 20% in MC4R-expressing HEK293 cell membranes, but shows no effect on cAMP levels in MC3R- or MC5R-expressing membranes.
- In vivo activity: in CT-26 tumor-bearing BALB/c mice, subcutaneous injection (3, 10, or 30 mg/kg; once daily) showed protection against tumor-induced body weight loss.
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Medchemexpress LLC MARTINOSTAT HYDROCH 5 mg
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MARTINOSTAT HYDROCH 5MG
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Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.0% | 464.96 | 50 MG
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PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12. It binds to MMP-12, forming a complex and shows potency against MMP-13, MMP-8, MMP-9, and MMP-3. Its activity can be significantly influenced by the presence of acetohydroxamate (AH).
- Specific, non-peptidic, non-zinc chelating ligand
- Inhibitor of matrix metalloproteinase MMP-12
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- Activity affected by acetohydroxamate (AH)
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