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Filtered Search Results
Medchemexpress LLC GDF-15 Cynomolgus 100ug | 100ug
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Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor (TGF- ) superfamily GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1) placental transforming growth factor- (PTGFB) prostate-derived factor (PDF) and placental bone morphogenetic protein (PLAB) GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging cancer and metabolic processes GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET AKT ERK1/2 and phospholipase C (PLC )[1] GDF-15 Protein Cynomolgus (Biotinylated HEK293 Fc) has 112 amino acids expressed by HEK293 cells with N-terminal hFc tag
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Selleck Chemical LLC 8-Bromo-cAMP
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8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0 05 M and a PKA activator
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369769 TUG-770 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377923 ISIS 626112 SODIUM 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000384241 ATOMOXETINE HYDROCH 10MM 1ML
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Medchemexpress LLC C2/Complement C2 Mo 10ug
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Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1 resulting in the formation of two distinct fragments C2b and C2a The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b leading to the formation of C3 or C5 convertase C2/Complement C2 Protein Mouse (HEK293 His) is the recombinant mouse-derived C2/Complement C2 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000453972 PTP INHIBITOR 1 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000453940 1-BROMO-3-CHLOROBENZ 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000373330 AS-PATISIRAN SODIUM 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429779 3-BENZYL-6-BROMO-2-M 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429886 SALT ACTIVE ENDONUCL 5KU
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000453831 TSTU 25G
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Apexbio Technology LLC Pimasertib (AS-703026) 1236699-92-5 10mM (in 1mL DMSO)
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Pimasertib (AS-703026 CAS 1236699-92-5) is a small molecule inhibitor targeting MEK1/2 within the MEK/ERK signaling pathway which is frequently dysregulated in cancer due to oncogenic mutations Pimasertib binds to a specific allosteric site on MEK inhibiting its activity independently of ATP and thus blocking downstream signaling involved in cell proliferation and survival In vitro Pimasertib demonstrates antiproliferative effects in tumor cell lines harboring activating mutations or gene amplifications in the MEK/ERK pathway with reported IC50 values ranging from 5 nM to 2 M In vivo oral administration in xenograft mouse models resulted in dose-dependent tumor growth inhibition Pimasertib is studied for its potential to modulate oncogenic MEK/ERK signaling in preclinical and clinical cancer research
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eMolecules METHYLMETHYLSULFINYLMET 25G
5000163137 METHYLMETHYLSULFINYLMET 25G
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Cambridge Isotope Laboratories Dieldrin (13C12 98-99%) 100 ug/mL in nonane 1 2 mL
Dieldrin (13C12 98-99%) 100 ug/mL in nonane 1 2 mL
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