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Filtered Search Results
Medchemexpress LLC TA-02 | 1784751-19-4 | 99.9% | 333.33 g/mol | C20H13F2N3 | 1 ML
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TA-02 is a small-molecule inhibitor of p38 MAPK and an analog of SB 203580, reported to show potent biochemical activity (IC50 ≈ 20 nM). The compound is supplied with high purity and is offered in ready-to-use solution formats as well as solid quantities for research use in biochemical and cell-based assays.
- Potent p38 MAPK inhibition (IC50 ≈ 20 nM).
- High purity, suitable for research applications.
- Available as a 10 mM solution in DMSO for immediate use.
- Solid form available for custom dilution and formulation.
- Stable under recommended storage conditions for reliable results.
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Medchemexpress LLC Kras G12d Inhibitor 14 | 2765254-39-3 | 98.88% | C20H19F3N4OS | 1 ML
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KRAS G12D inhibitor 14 is a potent KRAS G12D inhibitor with a KD of 33 nM for binding to KRAS G12D protein. It decreases the active form of KRAS G12D (KRAS G12D-GTP) but not KRAS G13D. For research use only, not for sale to patients.
- Binds to KRAS G12D protein with a KD of 33 nM.
- Decreases the active form of KRAS G12D (KRAS G12D-GTP) but does not affect KRAS G13D.
- Shows antiproliferative activity with an IC50 of 2.1 μM against KRAS G12D-mutated cells.
- Causes efficient apoptosis in SW1990 and CT26 cancer cells.
- Down-regulates phosphorylated Raf and Erk in CT26 and SW1990 cancer cell lines.
- Exhibits significant antitumor efficacy in a CT26 tumor model with a tumor growth inhibition (TGI) of 42% or 53% at doses of 40 mg/kg or 60 mg/kg (i.p.), without apparent toxicity.
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Chemscene CHEMSCENE
5000580155 TETRAHYDRO-B-CARBOLINE 25G
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Medchemexpress LLC 2-BROMO-3-METHOXYCYC 500 mg
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2-BROMO-3-METHOXYCYC 500MG
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000561208 ZAP-70 D1C10E XPR RABBIT MAB I
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000559278 F4/80 BM8.1 RAT MAB
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Medchemexpress LLC 2 3 4 5-TETRAHYDRO-1 100G
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2 3 4 5-TETRAHYDRO-1 100G
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Medchemexpress LLC QUINIZARIN 100G
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QUINIZARIN 100G
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Medchemexpress LLC TIRON 100G
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TIRON 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000772507 2 4 6-TRIPYRIDIN-4- 10G
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Medchemexpress LLC 6-BROMO-2-HYDROXY-3- 25G
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6-BROMO-2-HYDROXY-3- 25G
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eMolecules 165534-43-0 | DEPBT | AstaTech | MFCD01236967 | 299.223 | C11H14N3O5P | 97.000 | CCOP(=O)(OCC)On1nnc2ccccc2c1=O | 100g | 384832716
DEPBT | AstaTech | 165534-43-0 | MFCD01236967 | 299.223 | C11H14N3O5P | 97.000 | CCOP(=O)(OCC)On1nnc2ccccc2c1=O | 100g | 384832716
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Medchemexpress LLC SODIUM SORBATE 5G
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SODIUM SORBATE 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000757002 R-DODECANOLACTONE 25G
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Medchemexpress LLC 1-BROMO-3-3-BROMOPR 500 mg
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1-BROMO-3-3-BROMOPR 500MG
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