Halophenols
- (184)
- (5)
- (51)
- (1)
- (3)
- (6)
- (91)
- (2)
- (20)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (198)
- (1)
- (3)
- (12)
- (23)
- (1)
- (31)
- (2)
- (1)
- (216)
- (1)
- (4)
- (2)
- (23)
- (3)
- (10)
- (50)
- (2)
- (4)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (7)
- (14)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (16)
- (2)
- (11)
- (28)
- (2)
- (18)
- (6)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (5)
- (2)
- (1)
- (1)
- (8)
- (1)
- (1)
- (1)
- (1)
- (19)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (7)
- (10)
- (1)
- (4)
- (5)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (4)
- (2)
- (1)
- (4)
- (1)
- (4)
- (1)
- (6)
- (1)
- (3)
- (1)
- (1)
- (23)
- (4)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (7)
- (30)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (10)
- (15)
- (15)
- (1)
- (12)
- (9)
- (4)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (3)
- (8)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (23)
- (5)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (7)
- (2)
- (2)
- (1)
- (1)
- (4)
- (5)
- (1)
- (1)
- (1)
- (13)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (14)
- (5)
- (1)
- (4)
- (17)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (2)
- (5)
- (25)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (2)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (2)
- (6)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (9)
- (6)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (5)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (6)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (5)
- (2)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (1)
- (2)
- (1)
- (3)
- (1)
- (4)
- (1)
- (1)
- (1)
- (5)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (12)
- (2)
- (1)
- (1)
- (10)
- (12)
- (9)
- (1)
- (2)
- (1)
- (1)
- (41)
- (75)
- (110)
- (2)
- (1)
- (4)
- (9)
- (1)
- (2)
- (7)
- (7)
- (7)
- (2)
- (3)
- (2)
- (3)
- (3)
- (1)
- (19)
- (2)
- (5)
- (19)
- (114)
- (188)
- (5)
- (96)
- (7)
- (1)
- (3)
- (6)
- (19)
- (2)
- (1)
- (215)
- (3)
- (8)
- (5)
- (2)
- (2)
- (2)
- (11)
- (6)
- (2)
- (47)
- (4)
- (3)
- (3)
- (2)
- (22)
- (1)
- (2)
- (22)
- (2)
- (2)
- (2)
- (2)
- (3)
- (3)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (3)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (2)
- (1)
- (6)
- (3)
- (4)
- (2)
- (2)
- (11)
- (1)
- (5)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (5)
- (2)
- (2)
- (3)
- (6)
- (2)
- (2)
- (2)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (3)
- (2)
- (5)
- (3)
- (4)
- (2)
- (1)
- (3)
- (2)
- (3)
- (6)
- (2)
- (1)
- (3)
- (5)
- (1)
- (4)
- (4)
- (3)
- (1)
- (6)
- (4)
- (3)
- (2)
- (3)
- (2)
- (2)
- (4)
- (2)
- (2)
- (2)
- (6)
- (1)
- (5)
- (1)
- (4)
- (6)
- (3)
- (1)
- (3)
- (3)
- (5)
- (5)
- (2)
- (1)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (3)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (3)
- (1)
Filtered Search Results
eMolecules AstaTech / 2-CHLORO-6-(TRIFLUOROMETHOXY)BENZONITRILE / 1g / 335877287 / 55872 / 95.000 / 1261779-40-1 / MFCD18393805 / 221.560 / C8H3ClF3NO
AstaTech / 2-CHLORO-6-(TRIFLUOROMETHOXY)BENZONITRILE / 1g / 335877287 / 55872 / 95.000 / 1261779-40-1 / MFCD18393805 / 221.560 / C8H3ClF3NO
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
MEDCHEMEXPRESS LLC M-110 5MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
501872740 M-110 5MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules N-CHLOROACETOXYSUCCINIMI 25G
5000161036 N-CHLOROACETOXYSUCCINIMI 25G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000427373 VANILLIN 100G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Aβ1-42 aggregation inhibitor 1 | 2439107-75-0 | 468.66 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Aβ1-42 aggregation inhibitor 1 inhibits AChE (acetylcholinesterase) and BuChE (butyrylcholinesterase) with IC50 values of 2.64 μM and 1.29 μM, respectively. It also inhibits self-mediated Aβ1-42 aggregation by 51.29% at a concentration of 25 μM. This compound has potential for research into anti-Alzheimer's disease.
- Inhibits AChE (acetylcholinesterase) with an IC50 of 2.64 μM.
- Inhibits BuChE (butyrylcholinesterase) with an IC50 of 1.29 μM.
- Inhibits self-mediated Aβ1-42 aggregation by 51.29% at 25 μM.
- Has potential for anti-Alzheimer's disease research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Pardoprunox hydrochloride | 269718-83-4 | 99.5% | 269.73 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Pardoprunox (SLV-308) hydrochloride is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively. It is for research use only.
- Potent but partial D2 receptor agonist (pEC50= 8.0 and pA2=8.4) with 50% efficacy on forskolin stimulated cAMP accumulation.
- Acts as a partial agonist at human recombinant dopamine D3 receptors in the induction of [(35)S]GTPgammaS binding (intrinsic activity of 67%; pEC50=9.2) and antagonizes dopamine induction of [(35)S]GTPgammaS binding (pA2=9.0).
- Acts as a full 5-HT1A receptor agonist on forskolin induced cAMP accumulation at cloned human 5-HT1A receptors, though with low potency (pEC50=6.3).
- Available in solid form and as a solution in DMSO.
- Underwent clinical trials for early stage Parkinson's disease and advanced stage Parkinson's disease.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Tk-129 | 3031476-73-7 | C15H23N5O2 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
TK-129 is an orally active, low-toxicity, and potent KDM5B inhibitor with a high affinity (IC50=44 nM). It demonstrates cardioprotective effects by inhibiting KDM5B and interfering with the KDM5B-associated Wnt pathway. In vitro studies, TK-129 reduces ang II-induced activation of cardiac fibroblasts. In vivo, it has been shown to reduce isoprenaline-induced myocardial remodelling and fibrosis. This compound is suitable for use in studies related to cardiovascular disease.
- Orally active
- Low-toxicity
- Potent KDM5B inhibitor
- High affinity (IC50=44 nM)
- Cardioprotective effects
- Inhibits KDM5B and blocks the KDM5B-associated Wnt pathway
- Reduces ang ii-induced activation of cardiac fibroblasts in vitro
- Reduces isoprenaline-induced myocardial remodelling and fibrosis in vivo
- Suitable for cardiovascular disease studies
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Arc186 sodium | 1 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
ARC186 sodium is an unconjugated 40KDa PEG aptamer with a sequence identical to ARC1905 sodium. This highly potent complement inhibitor functions by blocking the convertase-catalyzed activation of C5.
- Purity: 94.13%
- Appearance: Solid
- Color: White to off-white
- Active in immunology and inflammation pathways
- Inhibits the complement system
- Relevant for inflammation or immune system disease research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Lerociclib dihydrochloride | 2097938-59-3 | 98.5% | 547.52 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
- Produces a robust and sustained G1 arrest in CDK4/6 dependent cells with an EC50 of approximately 20 nM.
- Causes a dose-dependent increase of cells in the G1 phase and exhibits complete inhibition of RB phosphorylation.
- Produces robust inhibition of proliferation in various tumor cell lines including breast, melanoma, leukemia, and lymphoma with EC50 concentrations as low as 23 nM.
- Elicits tumor regression in HER2+ breast cancer models.
- Shows tumor growth inhibition in MCF7 xenograft models, with Lerociclib being significantly more efficacious than palbociclib at 50 mg/kg.
- Demonstrates high efficacy in the ER+ ZR-75-1 breast cancer xenograft model and NSCLC tumor model.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC (E)-CLX-0921 | 606932-81-4 | 98.2% | 519.57 | 1 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
(E)-CLX-0921 is an orally active PPARγ agonist, an E-isomer of CLX-0921, with an IC50 of 1.54 μM. It demonstrates potent antihyperglycemic activity and is utilized in the study of type 2 diabetes.
- Orally active PPARγ agonist
- Potent antihyperglycemic activity
- Used for the study of type 2 diabetes
- Purity: 98.17%
- Molecular weight: 519.57
- Appearance: Solid
- Color: White to off-white
- Stable under recommended storage conditions
- Shipped at room temperature (in continental US)
- Stored at 4°C, sealed, away from moisture (solid)
- Stored at -80°C for 6 months or -20°C for 1 month (in solvent)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules N-FLUOROBENZENESULFONIMID 250G
5000225580 N-FLUOROBENZENESULFONIMID 250G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 2-BROMO-1 1-DIETHOXYETHANE 5G
5000225469 2-BROMO-1 1-DIETHOXYETHANE 5G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 3 3-DIFLUOROCYCLOBUTANECAR 10G
5000161422 3 3-DIFLUOROCYCLOBUTANECAR 10G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 3-CARBAMOYLPHENYLBORONIC 10G
5000161449 3-CARBAMOYLPHENYLBORONIC 10G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC ODN 2088 sodium | DNA, d(P-thio)(T-C-C-T-G-G-C-G-G-G-G-A-A-G-T), sodium salt | 1 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
ODN 2088 sodium is a potent inhibitor of TLR3, TLR7, and TLR9, showing no cytotoxic effects and inhibiting the release of IFN-α and IL-6. This product is for research use only.
- Purity: 98.82%
- Molecular weight (free acid): 4878
- Appearance: White to off-white solid
- Soluble in H2O at ≥ 25 mg/mL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More