Carboxylic acid esters
Medchemexpress LLC Trimebutine (maleate) | 34140-59-5 | 99.66% | 5 G
Trimebutine (maleate) | 34140-59-5 | 99.66% | 5 G
Medchemexpress LLC Trimebutine (maleate) | 34140-59-5 | 99.7% | 1 ML
Trimebutine (maleate) | 34140-59-5 | 99.7% | 1 ML
Medchemexpress LLC Trimebutine maleate | 34140-59-5 | 99.7% | 1 G
Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. It inhibits L-type Ca2+ and large-conductance calcium-activated potassium channels, blocking ion influx and efflux. It also targets Toll-like receptors, suppressing signals and inhibiting LPS-induced IRAK1, ERK1/2, JNK, and NF-κB activation for anti-inflammatory effects. It induces tumor cell apoptosis via AKT/ERK pathway inhibition and prevents excessive smooth muscle contraction, making it useful for gastrointestinal disorder studies.
- Multi-target inhibitor and opioid receptor agonist
- Exhibits antimuscarinic activity
- Blocks calcium influx and potassium ion efflux
- Suppresses Toll-like receptor signals
- Provides anti-inflammatory effects
- Induces tumor cell apoptosis
- Inhibits excessive smooth muscle contraction
- Useful in gastrointestinal disorder research
Medchemexpress LLC HY-50904 1g , BIBF 1120 Nintedanib CAS:656247-17-5 Purity:98%
Medchemexpress, HY-50904 1g BIBF 1120 Nintedanib CAS:656247-17-5 Formula:C31H33N5O4 IC50: 34 nM (VEGFR1), 13 nM (VEGFR2), 13 nM (VEGFR3), 69 nM (FGFR1), 37 nM (FGFR1), 108 nM (FGFR1), 59 nM (PDGFRα), 65 nM (PDGFRβ) Purity:98% BIBF 1120 is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRα/β with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-50904 200mg Medchemexpress, Nintedanib CAS:656247-17-5 Purity:>98%
Medchemexpress, HY-50904 200mg Nintedanib CAS:656247-17-5 Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.